ID   GLTPB_XENLA             Reviewed;         209 AA.
AC   Q6NU44;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Glycolipid transfer protein B;
DE            Short=GLTP-B;
GN   Name=gltp-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Accelerates the intermembrane transfer of various
CC       glycolipids. Catalyzes the transfer of various glycosphingolipids
CC       between membranes but does not catalyze the transfer of phospholipids.
CC       May be involved in the intracellular translocation of glucosylceramides
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GLTP family. {ECO:0000305}.
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DR   EMBL; BC068757; AAH68757.1; -; mRNA.
DR   RefSeq; NP_001084618.1; NM_001091149.1.
DR   AlphaFoldDB; Q6NU44; -.
DR   SMR; Q6NU44; -.
DR   DNASU; 414574; -.
DR   GeneID; 414574; -.
DR   KEGG; xla:414574; -.
DR   CTD; 414574; -.
DR   Xenbase; XB-GENE-6078013; gltp.L.
DR   OMA; VINDMNG; -.
DR   OrthoDB; 1160303at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 414574; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0120013; F:lipid transfer activity; IEA:InterPro.
DR   Gene3D; 1.10.3520.10; -; 1.
DR   InterPro; IPR036497; GLTP_sf.
DR   InterPro; IPR014830; Glycolipid_transfer_prot_dom.
DR   Pfam; PF08718; GLTP; 1.
DR   SUPFAM; SSF110004; SSF110004; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Lipid transport; Reference proteome; Repeat; Transport.
FT   CHAIN           1..209
FT                   /note="Glycolipid transfer protein B"
FT                   /id="PRO_0000343612"
FT   REPEAT          45..55
FT                   /note="1"
FT   REPEAT          56..66
FT                   /note="2"
FT   REGION          45..66
FT                   /note="2 X 12 AA approximate tandem repeats"
FT   BINDING         48..55
FT                   /ligand="beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-
FT                   N-[(9Z)-octadecenoyl]-sphing-4-enine"
FT                   /ligand_id="ChEBI:CHEBI:131557"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NZD2"
FT   BINDING         140
FT                   /ligand="beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-
FT                   N-[(9Z)-octadecenoyl]-sphing-4-enine"
FT                   /ligand_id="ChEBI:CHEBI:131557"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NZD2"
FT   BINDING         207
FT                   /ligand="beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-
FT                   N-[(9Z)-octadecenoyl]-sphing-4-enine"
FT                   /ligand_id="ChEBI:CHEBI:131557"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NZD2"
SQ   SEQUENCE   209 AA;  23765 MW;  E43D12E6CC6B3E29 CRC64;
     MAVLLLHQFK ALPADKQIDT CSFLDSVSHL PAFFDCLGSA IFSPIKADIT GNITKIRSVY
     ESNPTQFKTL QMILEGEKEL YGPKWPKAGA TLALMWLKRG LKFIQVLLQS ISDGERDDQN
     PNLIKVNITK AYDIALKNYH GWLVQKFFQT ALIAAPYKDD FLKALSKGQA VKEEECIEKI
     RKFLVNYTTT IEAIYIMYNK MNAELDYKA