ID   GLTR1_MYCBO             Reviewed;         256 AA.
AC   P0A5A0; A0A1R3Y2Q6; Q50459; X2BMC2;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=PGL/p-HBAD biosynthesis glycosyltransferase Mb2981;
DE            EC=2.4.1.-;
GN   OrderedLocusNames=BQ2027_MB2981;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Involved in glycosylation steps downstream of mono-O-methyl-
CC       glycosyl-p-hydroxybenzoic acid derivative (p-HBAD I) and 2-O-methyl-
CC       rhamnosyl-phenolphthiocerol dimycocerosate (mycoside B) during the p-
CC       hydroxybenzoic acid derivatives (p-HBAD) and glycosylated
CC       phenolphthiocerol dimycocerosates (PGL) biosynthesis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=SIU01603.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; LT708304; SIU01603.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_856626.1; NC_002945.3.
DR   AlphaFoldDB; P0A5A0; -.
DR   SMR; P0A5A0; -.
DR   EnsemblBacteria; SIU01603; SIU01603; BQ2027_MB2981.
DR   PATRIC; fig|233413.5.peg.3275; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Transferase.
FT   CHAIN           1..256
FT                   /note="PGL/p-HBAD biosynthesis glycosyltransferase Mb2981"
FT                   /id="PRO_0000059250"
SQ   SEQUENCE   256 AA;  29013 MW;  90C6EC628C59CA57 CRC64;
     MAAPMFSIII PTLNVAAVLP ACLDSIARQT CGDFELVLVD GGSTDETLDI ANIFAPNLGE
     RLIIHRDTDQ GVYDAMNRGV DLATGTWLLF LGADDSLYEA DTLARVAAFI GEHEPSDLVY
     GDVIMRSTNF RWGGAFDLDR LLFKRNICHQ AIFYRRGLFG TIGPYNLRYR VLADWDFNIR
     CFSNPALVTR YMHVVVASYN EFGGLSNTIV DKEFLKRLPM STRLGIRLVI VLVRRWPKVI
     SRAMVMRTVI SWRRRR