ID   GLTR1_MYCBP             Reviewed;         256 AA.
AC   A1KMV1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=PGL/p-HBAD biosynthesis glycosyltransferase BCG_2978;
DE            EC=2.4.1.-;
GN   OrderedLocusNames=BCG_2978;
OS   Mycobacterium bovis (strain BCG / Pasteur 1173P2).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=410289;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Pasteur 1173P2;
RX   PubMed=17372194; DOI=10.1073/pnas.0700869104;
RA   Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P.,
RA   Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K.,
RA   Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C.,
RA   Barrell B.G., Parkhill J., Cole S.T.;
RT   "Genome plasticity of BCG and impact on vaccine efficacy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007).
CC   -!- FUNCTION: Involved in glycosylation steps downstream of mono-O-methyl-
CC       glycosyl-p-hydroxybenzoic acid derivative (p-HBAD I) and 2-O-methyl-
CC       rhamnosyl-phenolphthiocerol dimycocerosate (mycoside B) during the p-
CC       hydroxybenzoic acid derivatives (p-HBAD) and glycosylated
CC       phenolphthiocerol dimycocerosates (PGL) biosynthesis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAL72967.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AM408590; CAL72967.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A1KMV1; -.
DR   SMR; A1KMV1; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   KEGG; mbb:BCG_2978; -.
DR   HOGENOM; CLU_025996_21_1_11; -.
DR   Proteomes; UP000001472; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Transferase.
FT   CHAIN           1..256
FT                   /note="PGL/p-HBAD biosynthesis glycosyltransferase
FT                   BCG_2978"
FT                   /id="PRO_0000314432"
SQ   SEQUENCE   256 AA;  29013 MW;  90C6EC628C59CA57 CRC64;
     MAAPMFSIII PTLNVAAVLP ACLDSIARQT CGDFELVLVD GGSTDETLDI ANIFAPNLGE
     RLIIHRDTDQ GVYDAMNRGV DLATGTWLLF LGADDSLYEA DTLARVAAFI GEHEPSDLVY
     GDVIMRSTNF RWGGAFDLDR LLFKRNICHQ AIFYRRGLFG TIGPYNLRYR VLADWDFNIR
     CFSNPALVTR YMHVVVASYN EFGGLSNTIV DKEFLKRLPM STRLGIRLVI VLVRRWPKVI
     SRAMVMRTVI SWRRRR