ID   GLUP_BRUA2              Reviewed;         412 AA.
AC   Q2YIJ8; Q44623; Q579Q5;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Glucose/galactose transporter;
GN   Name=gluP; OrderedLocusNames=BAB2_0184;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9168605; DOI=10.1099/00221287-143-5-1549;
RA   Essenberg R.C., Candler C., Nida S.K.;
RT   "Brucella abortus strain 2308 putative glucose and galactose transporter
RT   gene: cloning and characterization.";
RL   Microbiology 143:1549-1555(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- FUNCTION: Intake of glucose and galactose. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. FHS
CC       transporter (TC 2.A.1.7) family. {ECO:0000305}.
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DR   EMBL; U43785; AAB58958.1; -; Genomic_DNA.
DR   EMBL; AM040265; CAJ12350.1; -; Genomic_DNA.
DR   RefSeq; WP_002966392.1; NZ_KN046823.1.
DR   AlphaFoldDB; Q2YIJ8; -.
DR   SMR; Q2YIJ8; -.
DR   STRING; 359391.BAB2_0184; -.
DR   EnsemblBacteria; CAJ12350; CAJ12350; BAB2_0184.
DR   GeneID; 3827676; -.
DR   KEGG; bmf:BAB2_0184; -.
DR   PATRIC; fig|359391.11.peg.2134; -.
DR   HOGENOM; CLU_028452_2_2_5; -.
DR   OMA; TGMSMLY; -.
DR   PhylomeDB; Q2YIJ8; -.
DR   Proteomes; UP000002719; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005354; F:galactose transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR005964; Glc/Gal_transptr_bac.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR01272; gluP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..412
FT                   /note="Glucose/galactose transporter"
FT                   /id="PRO_0000094504"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        310..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        286
FT                   /note="A -> D (in Ref. 1; AAB58958)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        309
FT                   /note="N -> D (in Ref. 1; AAB58958)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        410
FT                   /note="S -> T (in Ref. 1; AAB58958)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   412 AA;  43801 MW;  769716191349FE21 CRC64;
     MATSIPTNNP LHTETSSQKN YGFALTSLTL LFFMWGFITC LNDILIPHLK NVFQLNYTQS
     MLIQFCFFGA YFIVSLPAGQ LVKRISYKRG IVVGLIVAAI GCALFIPAAS YRVYALFLGA
     LFVLASGVTI LQVAANPYVT ILGKPETAAS RLTLTQAFNS LGTTVAPVFG AVLILSAATD
     ATVNAEADAV RFPYLLLALA FTVLAIIFAI LKPPDVQEDE PALSDKKEGS AWQYRHLVLG
     AIGIFVYVGA EVSVGSFLVN FLSDPTVAGL SETDAAHHVA YFWGGAMVGR FIGSAAMRYI
     DDGKALAFNA FVAIILLFIT VATTGHIAMW SVLAIGLFNS IMFPTIFSLA LHGLGSHTSQ
     GSGILCLAIV GGAIVPLIQG ALADAIGIHL AFLMPIICYA YIAFYGLIGS KS