GLUP_BRUAB
ID GLUP_BRUAB Reviewed; 412 AA.
AC P0C105; Q44623; Q579Q5;
DT 07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Glucose/galactose transporter;
GN Name=gluP; OrderedLocusNames=BruAb2_0185;
OS Brucella abortus biovar 1 (strain 9-941).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=262698;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9-941;
RX PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT "Completion of the genome sequence of Brucella abortus and comparison to
RT the highly similar genomes of Brucella melitensis and Brucella suis.";
RL J. Bacteriol. 187:2715-2726(2005).
CC -!- FUNCTION: Intake of glucose and galactose. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. FHS
CC transporter (TC 2.A.1.7) family. {ECO:0000305}.
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DR EMBL; AE017224; AAX75629.1; -; Genomic_DNA.
DR RefSeq; WP_002966392.1; NC_006933.1.
DR AlphaFoldDB; P0C105; -.
DR SMR; P0C105; -.
DR TCDB; 2.A.1.7.2; the major facilitator superfamily (mfs).
DR EnsemblBacteria; AAX75629; AAX75629; BruAb2_0185.
DR GeneID; 3827676; -.
DR KEGG; bmb:BruAb2_0185; -.
DR HOGENOM; CLU_028452_2_2_5; -.
DR OMA; TGMSMLY; -.
DR Proteomes; UP000000540; Chromosome II.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005354; F:galactose transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005355; F:glucose transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR005964; Glc/Gal_transptr_bac.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR01272; gluP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..412
FT /note="Glucose/galactose transporter"
FT /id="PRO_0000094503"
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 310..330
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 412 AA; 43801 MW; 769716191349FE21 CRC64;
MATSIPTNNP LHTETSSQKN YGFALTSLTL LFFMWGFITC LNDILIPHLK NVFQLNYTQS
MLIQFCFFGA YFIVSLPAGQ LVKRISYKRG IVVGLIVAAI GCALFIPAAS YRVYALFLGA
LFVLASGVTI LQVAANPYVT ILGKPETAAS RLTLTQAFNS LGTTVAPVFG AVLILSAATD
ATVNAEADAV RFPYLLLALA FTVLAIIFAI LKPPDVQEDE PALSDKKEGS AWQYRHLVLG
AIGIFVYVGA EVSVGSFLVN FLSDPTVAGL SETDAAHHVA YFWGGAMVGR FIGSAAMRYI
DDGKALAFNA FVAIILLFIT VATTGHIAMW SVLAIGLFNS IMFPTIFSLA LHGLGSHTSQ
GSGILCLAIV GGAIVPLIQG ALADAIGIHL AFLMPIICYA YIAFYGLIGS KS
