ID   GLUP_HELPJ              Reviewed;         407 AA.
AC   Q9ZK41;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=Putative glucose/galactose transporter;
GN   Name=gluP; OrderedLocusNames=jhp_1101;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Intake of glucose and galactose. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. FHS
CC       transporter (TC 2.A.1.7) family. {ECO:0000305}.
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DR   EMBL; AE001439; AAD06674.1; -; Genomic_DNA.
DR   PIR; A71850; A71850.
DR   RefSeq; WP_001173109.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZK41; -.
DR   SMR; Q9ZK41; -.
DR   STRING; 85963.jhp_1101; -.
DR   EnsemblBacteria; AAD06674; AAD06674; jhp_1101.
DR   KEGG; hpj:jhp_1101; -.
DR   PATRIC; fig|85963.30.peg.1481; -.
DR   eggNOG; COG0738; Bacteria.
DR   OMA; TGMSMLY; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005354; F:galactose transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR005964; Glc/Gal_transptr_bac.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR01272; gluP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..407
FT                   /note="Putative glucose/galactose transporter"
FT                   /id="PRO_0000094507"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   407 AA;  43962 MW;  4B724910FB30D328 CRC64;
     MQKTSNTLAL GSLTALFFLM GFITVLNDIL IPHLKPIFDL TYFEASLIQF CFFGAYFIMG
     GVFGNVISKI GYPFGVVLGF VITASGCALF YPAAHFGSYG FFLGALFILA SGIVCLQTAG
     NPFVTLLSKG KEARNLVLVQ AFNSLGTTLG PIFGSLLIFS ATKTSDNLSL IDKLADAKSV
     QMPYLGLAVF SLLLALVMYL LKLPDVEKEM PKETTQKSLF SHKHFVFGAL GIFFYVGGEV
     AIGSFLVLSF EKLLNLDAQS SAHYLVYYWG GAMVGRFLGS ALMNKIAPNK YLAFNALSSI
     ILIALAILIG GKIALFALTF VGFFNSIMFP TIFSLATLNL GHLTSKASGV ISMAIVGGAL
     IPPIQGVVTD MLTATESNLL YAYSVPLLCY FYILFFALKG YKQEENS