ID   GLXA_RHIME              Reviewed;         324 AA.
AC   O87389;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=HTH-type transcriptional regulator GlxA;
GN   Name=glxA; OrderedLocusNames=R00086; ORFNames=SMc02609;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RA   Powers E.L., Vuyyuru V., Kahn M.L.;
RL   Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
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DR   EMBL; AF055582; AAC62219.1; -; Genomic_DNA.
DR   EMBL; AL591688; CAC41473.1; -; Genomic_DNA.
DR   RefSeq; NP_384192.1; NC_003047.1.
DR   RefSeq; WP_003536327.1; NC_003047.1.
DR   AlphaFoldDB; O87389; -.
DR   SMR; O87389; -.
DR   STRING; 266834.SMc02609; -.
DR   EnsemblBacteria; CAC41473; CAC41473; SMc02609.
DR   GeneID; 61601567; -.
DR   KEGG; sme:SMc02609; -.
DR   PATRIC; fig|266834.11.peg.1443; -.
DR   eggNOG; COG4977; Bacteria.
DR   HOGENOM; CLU_000445_59_0_5; -.
DR   OMA; PFELACA; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF52317; SSF52317; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..324
FT                   /note="HTH-type transcriptional regulator GlxA"
FT                   /id="PRO_0000194523"
FT   DOMAIN          223..321
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        240..261
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        288..311
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   324 AA;  34960 MW;  4D622F5473575D0D CRC64;
     MAASSDSRNV QRIGFLLVRN FALMSYASAT EPLRAANLLA GRPLYQIVPL APGGGTVASS
     SGLSVGCADL ESEGESCHTV FVCAGGEPTD WADTSASHTT LRRLSRLGIR IGGISSGAFV
     LAAAGLLDNR DFTIHWEHAP ALKEAFPHLN PRHARFVLDG GIATCGGGVA PLDMMHAMIA
     ERLGTDFARR VSDWYLHAAV AEPAAPQRGS AAERFGTNHP ALLAVLEKME TAIERPLDRT
     AMARLAGVSP RHLDRLFREH RGTGFLDTYR EIRLRHARRL LQQSPLSIPE IAYATGFSSP
     AHFSNAFKRL FSQTPGSLRR RSGS