ID   GLXK_BACSU              Reviewed;         382 AA.
AC   P42100;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 2.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Glycerate kinase;
DE            EC=2.7.1.31;
GN   Name=glxK; Synonyms=yxaA; OrderedLocusNames=BSU40040; ORFNames=S14A;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / BGSC1A1;
RX   PubMed=7584049; DOI=10.1093/dnares/2.2.61;
RA   Yoshida K., Seki S., Fujimura M., Miwa Y., Fujita Y.;
RT   "Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome
RT   between the gnt and iol operons.";
RL   DNA Res. 2:61-69(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE REVISION TO 193.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-13.
RX   PubMed=3020045; DOI=10.1016/s0021-9258(18)67083-8;
RA   Fujita Y., Fujita T., Miwa Y., Nihashi J., Aratani Y.;
RT   "Organization and transcription of the gluconate operon, gnt, of Bacillus
RT   subtilis.";
RL   J. Biol. Chem. 261:13744-13753(1986).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+);
CC         Xref=Rhea:RHEA:23516, ChEBI:CHEBI:15378, ChEBI:CHEBI:16659,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216;
CC         EC=2.7.1.31;
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-1 family.
CC       {ECO:0000305}.
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DR   EMBL; AB005554; BAA21580.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB16041.2; -; Genomic_DNA.
DR   EMBL; J02584; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; X03510; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A70071; A70071.
DR   RefSeq; NP_391884.2; NC_000964.3.
DR   RefSeq; WP_003242551.1; NZ_JNCM01000034.1.
DR   AlphaFoldDB; P42100; -.
DR   SMR; P42100; -.
DR   STRING; 224308.BSU40040; -.
DR   PaxDb; P42100; -.
DR   PRIDE; P42100; -.
DR   EnsemblBacteria; CAB16041; CAB16041; BSU_40040.
DR   GeneID; 937708; -.
DR   KEGG; bsu:BSU40040; -.
DR   PATRIC; fig|224308.179.peg.4331; -.
DR   eggNOG; COG1929; Bacteria.
DR   InParanoid; P42100; -.
DR   OMA; YTAVHEK; -.
DR   PhylomeDB; P42100; -.
DR   BioCyc; BSUB:BSU40040-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008887; F:glycerate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031388; P:organic acid phosphorylation; IEA:InterPro.
DR   Gene3D; 3.40.50.10350; -; 1.
DR   Gene3D; 3.90.1510.10; -; 1.
DR   InterPro; IPR018193; Glyc_kinase_flavodox-like_fold.
DR   InterPro; IPR004381; Glycerate_kinase.
DR   InterPro; IPR018197; Glycerate_kinase_RE-like.
DR   InterPro; IPR036129; Glycerate_kinase_sf.
DR   PANTHER; PTHR21599; PTHR21599; 1.
DR   Pfam; PF02595; Gly_kinase; 1.
DR   PIRSF; PIRSF006078; GlxK; 1.
DR   SUPFAM; SSF110738; SSF110738; 1.
DR   TIGRFAMs; TIGR00045; TIGR00045; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Kinase; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..382
FT                   /note="Glycerate kinase"
FT                   /id="PRO_0000071534"
FT   CONFLICT        193
FT                   /note="D -> N (in Ref. 1; BAA21580)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   382 AA;  39400 MW;  18E687B3CE30B4DF CRC64;
     MKIIIAPDSF KESLSALEAA EAIERGFKSV FPGADYRKLP VADGGEGTVQ SLVDATNGRI
     IEQVVTGPLG EPVRAFFGMM GDGRTAVIEM AAASGLHLVP VDKRNPLITT TRGTGELIGA
     ALDAGAERLI IGIGGSATND GGAGMIQALG GRLLDNSGSE IGPGGGALSQ LASIDVSGLD
     SRLRNVKLEV ACDVDNPLTG PKGATAVFGP QKGATADMLD VLDQNVSHFA DMAEKALGST
     FRDTEGAGAA GGLGWSLLTY LQADLKRGID IVLEAVDFES IVQDADLVIT GEGRIDSQTV
     HGKTPIGVAK AAKSYDVPVI GIAGSISRDS NAVYQHGIDA LFSIVPGAVP LEDAFEHAAE
     YMERTARDIA ASIKLAKTMF LI