ID   GLXK_HAEIN              Reviewed;         378 AA.
AC   P44507;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Glycerate kinase;
DE            EC=2.7.1.31;
GN   Name=glxK; OrderedLocusNames=HI_0091;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+);
CC         Xref=Rhea:RHEA:23516, ChEBI:CHEBI:15378, ChEBI:CHEBI:16659,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216;
CC         EC=2.7.1.31;
CC   -!- SIMILARITY: Belongs to the glycerate kinase type-1 family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC21769.1; -; Genomic_DNA.
DR   PIR; C64142; C64142.
DR   RefSeq; NP_438264.1; NC_000907.1.
DR   RefSeq; WP_005649699.1; NC_000907.1.
DR   AlphaFoldDB; P44507; -.
DR   SMR; P44507; -.
DR   STRING; 71421.HI_0091; -.
DR   EnsemblBacteria; AAC21769; AAC21769; HI_0091.
DR   KEGG; hin:HI_0091; -.
DR   PATRIC; fig|71421.8.peg.92; -.
DR   eggNOG; COG1929; Bacteria.
DR   HOGENOM; CLU_028255_0_0_6; -.
DR   OMA; CRFEVAC; -.
DR   PhylomeDB; P44507; -.
DR   BioCyc; HINF71421:G1GJ1-96-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008887; F:glycerate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031388; P:organic acid phosphorylation; IEA:InterPro.
DR   Gene3D; 3.40.50.10350; -; 1.
DR   Gene3D; 3.90.1510.10; -; 1.
DR   InterPro; IPR018193; Glyc_kinase_flavodox-like_fold.
DR   InterPro; IPR004381; Glycerate_kinase.
DR   InterPro; IPR018197; Glycerate_kinase_RE-like.
DR   InterPro; IPR036129; Glycerate_kinase_sf.
DR   PANTHER; PTHR21599; PTHR21599; 1.
DR   Pfam; PF02595; Gly_kinase; 1.
DR   PIRSF; PIRSF006078; GlxK; 1.
DR   SUPFAM; SSF110738; SSF110738; 1.
DR   TIGRFAMs; TIGR00045; TIGR00045; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Kinase; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..378
FT                   /note="Glycerate kinase"
FT                   /id="PRO_0000071533"
SQ   SEQUENCE   378 AA;  39759 MW;  EBC57937BD8838A9 CRC64;
     MKFVIAPDSF KESLTALEVA TAIETGFKRV FPDADYVKLP MADGGEGTVQ SLVDATQGKL
     IECEVTAPLG DKVKSFFGLS GDGKTAIIEM AAASGLHLVP PEKRNPLLTT SYGTGELIKL
     ALDLGVESFI LGIGGSATND GGVGMLQALG MQCLDSQDKP IGFGGAELAN IVKIDVQQLD
     PRLQQVHIEV ACDVNNPLCG ECGASAIFGP QKGATPEMVK QLDAALSHFA EIAERDCGKQ
     IRDQAGAGAA GGMGGGLLLL PSVQLKAGIQ IVLDRLHLID YVKDADVVIT GEGRIDAQSI
     MGKTPIGVAR TAKQFNKPVI AIAGCLREDY DVVFDHGIDA VFPIIHQLGD LSDILKQGEQ
     NLISTAQNVA RVLAFKFH