ID   AMIF_STRPN              Reviewed;         308 AA.
AC   P18766;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   26-SEP-2001, sequence version 2.
DT   03-AUG-2022, entry version 135.
DE   RecName: Full=Oligopeptide transport ATP-binding protein AmiF;
GN   Name=amiF; OrderedLocusNames=SP_1887;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=R6 / R800;
RX   PubMed=2352474; DOI=10.1111/j.1365-2958.1990.tb00632.x;
RA   Alloing G., Trombe M.C., Claverys J.-P.;
RT   "The ami locus of the Gram-positive bacterium Streptococcus pneumoniae is
RT   similar to binding protein-dependent transport operons of Gram-negative
RT   bacteria.";
RL   Mol. Microbiol. 4:633-644(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       oligopeptides. Probably responsible for energy coupling to the
CC       transport system.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; X17337; CAA35217.1; -; Genomic_DNA.
DR   EMBL; AE005672; AAK75958.1; -; Genomic_DNA.
DR   PIR; E95220; E95220.
DR   PIR; S11153; S11153.
DR   RefSeq; WP_001291293.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; P18766; -.
DR   SMR; P18766; -.
DR   STRING; 170187.SP_1887; -.
DR   EnsemblBacteria; AAK75958; AAK75958; SP_1887.
DR   KEGG; spn:SP_1887; -.
DR   eggNOG; COG4608; Bacteria.
DR   OMA; VACHWAE; -.
DR   PhylomeDB; P18766; -.
DR   BioCyc; SPNE170187:G1FZB-1917-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013563; Oligopep_ABC_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08352; oligo_HPY; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Peptide transport; Protein transport; Transport.
FT   CHAIN           1..308
FT                   /note="Oligopeptide transport ATP-binding protein AmiF"
FT                   /id="PRO_0000091929"
FT   DOMAIN          6..251
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         42..49
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   CONFLICT        132
FT                   /note="N -> S (in Ref. 1; CAA35217)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        271..272
FT                   /note="DP -> EG (in Ref. 1; CAA35217)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   308 AA;  34797 MW;  51EE1EBA11915709 CRC64;
     MSEKLVEIKD LEISFGEGSK KFVAVKNANF FINKGETFSL VGESGSGKTT IGRAIIGLND
     TSNGDIIFDG QKINGKKSRE QAAELIRRIQ MIFQDPAASL NERATVDYII SEGLYNHRLF
     KDEEERKEKV QNIIREVGLL AEHLTRYPHE FSGGQRQRIG IARALVMQPD FVIADEPISA
     LDVSVRAQVL NLLKKFQKEL GLTYLFIAHD LSVVRFISDR IAVIYKGVIV EVAETEELFN
     NPIHPYTQAL LSAVPIPDPI LERKKVLKVY DPSQHDYETD KPSMVEIRPG HYVWANQAEL
     ARYQKGLN