AMMR1_MOUSE
ID AMMR1_MOUSE Reviewed; 344 AA.
AC Q9JHT5;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Nuclear protein AMMECR1 {ECO:0000305};
DE AltName: Full=AMME syndrome candidate gene 1 protein homolog;
GN Name=Ammecr1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Embryo;
RX PubMed=10828604; DOI=10.1159/000015533;
RA Vitelli F., Meloni I., Fineschi S., Favara F., Tiziana Storlazzi C.,
RA Rocchi M., Renieri A.;
RT "Identification and characterization of mouse orthologs of the AMMECR1 and
RT FACL4 genes deleted in AMME syndrome: orthology of Xq22.3 and MmuXF1-F3.";
RL Cytogenet. Cell Genet. 88:259-263(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Spinal ganglion;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y4X0}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ243485; CAB95767.1; -; mRNA.
DR EMBL; AK051736; BAC34745.1; -; mRNA.
DR CCDS; CCDS30452.1; -.
DR RefSeq; NP_062369.1; NM_019496.3.
DR AlphaFoldDB; Q9JHT5; -.
DR SMR; Q9JHT5; -.
DR STRING; 10090.ENSMUSP00000036085; -.
DR iPTMnet; Q9JHT5; -.
DR PhosphoSitePlus; Q9JHT5; -.
DR EPD; Q9JHT5; -.
DR MaxQB; Q9JHT5; -.
DR PaxDb; Q9JHT5; -.
DR PeptideAtlas; Q9JHT5; -.
DR PRIDE; Q9JHT5; -.
DR ProteomicsDB; 296029; -.
DR Antibodypedia; 29496; 131 antibodies from 23 providers.
DR DNASU; 56068; -.
DR Ensembl; ENSMUST00000041317; ENSMUSP00000036085; ENSMUSG00000042225.
DR GeneID; 56068; -.
DR KEGG; mmu:56068; -.
DR UCSC; uc009umc.1; mouse.
DR CTD; 9949; -.
DR MGI; MGI:1860206; Ammecr1.
DR VEuPathDB; HostDB:ENSMUSG00000042225; -.
DR eggNOG; KOG3274; Eukaryota.
DR GeneTree; ENSGT00390000010397; -.
DR HOGENOM; CLU_052828_0_0_1; -.
DR InParanoid; Q9JHT5; -.
DR OMA; MAYAEYI; -.
DR OrthoDB; 1274811at2759; -.
DR PhylomeDB; Q9JHT5; -.
DR TreeFam; TF314680; -.
DR BioGRID-ORCS; 56068; 4 hits in 71 CRISPR screens.
DR ChiTaRS; Ammecr1; mouse.
DR PRO; PR:Q9JHT5; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q9JHT5; protein.
DR Bgee; ENSMUSG00000042225; Expressed in hair follicle and 125 other tissues.
DR Genevisible; Q9JHT5; MM.
DR GO; GO:0005739; C:mitochondrion; ISO:MGI.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR Gene3D; 3.30.700.20; -; 1.
DR InterPro; IPR023473; AMMECR1.
DR InterPro; IPR036071; AMMECR1_dom_sf.
DR InterPro; IPR002733; AMMECR1_domain.
DR InterPro; IPR027485; AMMECR1_N.
DR PANTHER; PTHR13016; PTHR13016; 1.
DR Pfam; PF01871; AMMECR1; 1.
DR SUPFAM; SSF143447; SSF143447; 1.
DR TIGRFAMs; TIGR00296; TIGR00296; 1.
DR PROSITE; PS51112; AMMECR1; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..344
FT /note="Nuclear protein AMMECR1"
FT /id="PRO_0000142367"
FT DOMAIN 130..324
FT /note="AMMECR1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00467"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 16
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y4X0"
SQ SEQUENCE 344 AA; 36031 MW; BA35788884DF393D CRC64;
MAAGCCGVKK QKLSSSPPSG SGGGGGASSS SHCSGESQCR AGELGLGGAG TRLNGLGGLS
GGGGSGGGGG CPLSPPQGCG GGGGGGGGGG SGSGGGGISL SPPLSCGVGT LLSTPAAATA
SSPSSSSSSP GSRKMVVSAE MCCFCFDVLY CHLYGYQQPR TPRFTNEPYP LFVTWKIGRD
KRLRGCIGTF SAMNLHSGLR EYTLTSALKD SRFPPMTRDE LPRLFCSVSL LTNFEDVCDY
LDWEVGVHGI RIEFINEKGS KRTATYLPEV AKEQGWDHIQ TIDSLLRKGG YKAPITNEFR
KTIKLTRYRS EKMTLSYAEY LAHRQHHHFQ NGIGHPLPPY NHYS
