AMO1_SCHPO
ID AMO1_SCHPO Reviewed; 475 AA.
AC O74315;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Nucleoporin-like protein amo1;
DE AltName: Full=Aberrant microtubule protein 1;
GN Name=amo1; ORFNames=SPBC15D4.10c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=15797925; DOI=10.1242/jcs.02305;
RA Pardo M., Nurse P.;
RT "The nuclear rim protein Amo1 is required for proper microtubule
RT cytoskeleton organisation in fission yeast.";
RL J. Cell Sci. 118:1705-1714(2005).
CC -!- FUNCTION: Involved in the cell polarity process where it is required
CC for the correct termination of microtubule growth at the cell ends
CC during interphase. {ECO:0000269|PubMed:15797925}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15797925}.
CC Note=Nucleus; nuclear rim.
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DR EMBL; CU329671; CAA20485.1; -; Genomic_DNA.
DR PIR; T39486; T39486.
DR RefSeq; NP_596250.1; NM_001022169.2.
DR AlphaFoldDB; O74315; -.
DR BioGRID; 276456; 107.
DR STRING; 4896.SPBC15D4.10c.1; -.
DR iPTMnet; O74315; -.
DR MaxQB; O74315; -.
DR PaxDb; O74315; -.
DR EnsemblFungi; SPBC15D4.10c.1; SPBC15D4.10c.1:pep; SPBC15D4.10c.
DR GeneID; 2539911; -.
DR KEGG; spo:SPBC15D4.10c; -.
DR PomBase; SPBC15D4.10c; amo1.
DR VEuPathDB; FungiDB:SPBC15D4.10c; -.
DR eggNOG; KOG0845; Eukaryota.
DR HOGENOM; CLU_575103_0_0_1; -.
DR InParanoid; O74315; -.
DR OMA; EWIFSAY; -.
DR Reactome; R-SPO-159227; Transport of the SLBP independent Mature mRNA.
DR Reactome; R-SPO-159231; Transport of Mature mRNA Derived from an Intronless Transcript.
DR Reactome; R-SPO-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR Reactome; R-SPO-3232142; SUMOylation of ubiquitinylation proteins.
DR Reactome; R-SPO-4085377; SUMOylation of SUMOylation proteins.
DR Reactome; R-SPO-4551638; SUMOylation of chromatin organization proteins.
DR Reactome; R-SPO-4570464; SUMOylation of RNA binding proteins.
DR Reactome; R-SPO-5578749; Transcriptional regulation by small RNAs.
DR PRO; PR:O74315; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR GO; GO:0034399; C:nuclear periphery; IDA:PomBase.
DR GO; GO:0005643; C:nuclear pore; IDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR InterPro; IPR000571; Znf_CCCH.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Cell cycle; Cell division; Metal-binding; Nucleus; Reference proteome;
KW Zinc; Zinc-finger.
FT CHAIN 1..475
FT /note="Nucleoporin-like protein amo1"
FT /id="PRO_0000064588"
FT ZN_FING 1..25
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 165..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 51792 MW; BF8567581869C74C CRC64;
MVVCKYFLQN RCRYGTNCKN QHTVPSNGQN AFSKVNVFRP ENGRPPIWVQ RRLKRSDLDN
LLPNRRMKDI NDDLKNAKPQ WPFTGYSVVE NLPSIYEGDV SPEELRWWAY QAKATNNMQA
YEQRQKQLMD DVEAKAAAVK RSPAAAFDEM RNKLVGKTNY KSIFDKSTSN STVTSNQFNK
PTQNSPFNSF SNNNNSFNNN QQANDIFGAP TTSAFTSQLN ASPFSQNTSS NSFTGSNPVQ
NNPSSFGSSS FGSATSGPSA FGGISQPNSS FVNSGQGIPN SSFSSFSQVA SGFSQSQNVN
DPSSIFGPTV ASGFGIQNQP QQSAFQNLNT QFSLPNNSQP VFGHTSLTQP VNPNGFTVQP
PATFMQQPQG PFVPPNTTFE SPFANVTSKI SASGFSNDNP ANKNIIQTPM FGSSNTIDGP
INPIGASSIQ TLDDQVEMSN SNQNLAFPPE MIQQFEAQDF IPGKVPTTAP PPQFC
