ID   GLYCO_SHRV              Reviewed;         512 AA.
AC   Q9QJT6;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   29-SEP-2021, entry version 69.
DE   RecName: Full=Glycoprotein;
DE   Flags: Precursor;
GN   Name=G;
OS   Snakehead rhabdovirus (SHRV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Gammarhabdovirinae;
OC   Novirhabdovirus.
OX   NCBI_TaxID=103603;
OH   NCBI_TaxID=203314; Gobiosoma bosc (Naked goby) (Gobius bosc).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Johnson M.C., Bell R.H., Leong J.C.;
RT   "The complete genomic sequence of snakehead rhabdovirus.";
RL   Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Attaches the virus to host cellular receptor, inducing
CC       endocytosis of the virion. In the endosome, the acidic pH induces
CC       conformational changes in the glycoprotein trimer, which trigger fusion
CC       between virus and cell membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. Interacts with matrix protein (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass type I
CC       membrane protein {ECO:0000250}.
CC   -!- PTM: Glycosylated by host. Glycosylation is crucial for glycoprotein
CC       export at the cell surface (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the novirhabdovirus glycoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; AF147498; AAD56769.1; -; Genomic_RNA.
DR   RefSeq; NP_050583.1; NC_000903.1.
DR   GeneID; 1457772; -.
DR   KEGG; vg:1457772; -.
DR   Proteomes; UP000007219; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001903; Rhabd_glycop.
DR   InterPro; IPR002417; Spike_prot.
DR   Pfam; PF00974; Rhabdo_glycop; 1.
DR   PRINTS; PR00796; SPIKEPROTEIN.
PE   3: Inferred from homology;
KW   Glycoprotein; Host-virus interaction; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix; Viral attachment to host cell;
KW   Viral envelope protein; Virion; Virus entry into host cell.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..512
FT                   /note="Glycoprotein"
FT                   /id="PRO_0000299232"
FT   TOPO_DOM        26..463
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        464..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        487..512
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   512 AA;  58079 MW;  FD82952A6E861CA4 CRC64;
     MTLPNMKPKR IVLFLVFLNA WVSNAQVTHK PRPDSIVEYS EEWENPIYTT PSHCFEDTFA
     PVKPEKLRCP HIFDDQNLGL TASKAKILHM DLKPEDTHFE AKGRLLHKVT YQVLCSTGFF
     GGRTVTRKVL ETPMGDNEAQ AYKAVDREFP YFPEPLCFWL RDNVAAERVF HFSTPKTVTV
     DLYSRKYISP DFVGGQCAKS PCPTHWPNVY WVGETQSPEC PSIDTEGGHI FTKKDTHRIT
     KAVVHGHHPW GLTKACQIQF CNEQWIRTDL GDLIRIEPND GTSSLTLPKC QDNVVQMRGN
     LDDFSYLNHA IVNMAQRSEC LEAHSSIVAQ QKVSPYLLSK FRPPHPGLGK AHYLQNNTIM
     RGDCIYEGVA EISENRTTYR NLKGEWKKWS LSRGGEGYDG MTVGTKIVIP DLEKYQSIYD
     NGMFIPKLLG EVPHPSIVIT YNQTDSIETG IFTDGKLLNM GVNWTLWPSL SGISLFTVAS
     LILIWYCCCR VTPQALNYSI PMHTITSRGV EI