ID   GLYCO_SIGMA             Reviewed;         526 AA.
AC   P12647;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   23-FEB-2022, entry version 77.
DE   RecName: Full=Spike glycoprotein;
DE   Flags: Precursor;
GN   Name=G;
OS   Sigma virus.
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; unclassified Rhabdoviridae.
OX   NCBI_TaxID=11301;
OH   NCBI_TaxID=7227; Drosophila melanogaster (Fruit fly).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2822842; DOI=10.1099/0022-1317-68-10-2625;
RA   Teninges D., Bras-Herreng F.;
RT   "Rhabdovirus sigma, the hereditary CO2 sensitivity agent of Drosophila:
RT   nucleotide sequence of a cDNA clone encoding the glycoprotein.";
RL   J. Gen. Virol. 68:2625-2638(1987).
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X06171; CAA29536.1; -; Genomic_RNA.
DR   PIR; A27150; VGVNSG.
DR   SMR; P12647; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001903; Rhabd_glycop.
DR   Pfam; PF00974; Rhabdo_glycop; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Host-virus interaction; Membrane; Signal;
KW   Viral attachment to host cell; Virion; Virus entry into host cell.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..526
FT                   /note="Spike glycoprotein"
FT                   /id="PRO_0000040999"
FT   CARBOHYD        32
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        445
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        459
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   526 AA;  59011 MW;  335607C69249DD9D CRC64;
     MLALIFITTS VWLAASQKTF TPDLVFPEMN RNSSWSVANY GEILCPTSFQ SYEPKKHQIL
     TRVLVERPSL NTDTKVEGYT CHKVKYETIC DMPWYFSPTI SHSISPLRVK ESECKDAIAE
     HQLGTHVSLS FPPEDCSWNS VNTKAYEDII VKDHPVMLDP YTNNYVDAIF PGGISSPGMG
     GTIHDDMMWV SKDLAVSPEC SGGNKVWGLF IHLGCMGGGS RCWKSAPPHR GPQGQEPHFS
     LPVSFYNKIG VRFHDGEWMK VSVNLDHPNS VTFQVTDFPP CPPGTTIQTA VVENINPEIQ
     ELTVNMMYRL KCQETISKMV SGLPTSVFDL SYLIQVQEGP SIVYKREKGV LYQSVGMYQY
     IDTVTLNTEE NQLGENARGQ KVFWTEWSDS PTRPDPQEGS NGFFKYEGQI RVPLGMSLRL
     EAATELMWGH PVHTVSHPIL HVISNHTEQS VTTWNRGVNS TNLIGQATRS ISGFYNDLKL
     YLILALIVVS IVALVVLDVI PFKYILFILC PPLLLCRFIK CSTKEA