ID   GLYCO_TAVCV             Reviewed;         588 AA.
AC   Q5GA86;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Glycoprotein;
DE   Flags: Precursor;
GN   Name=G;
OS   Taro vein chlorosis virus (TAVCV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Betarhabdovirinae;
OC   Alphanucleorhabdovirus.
OX   NCBI_TaxID=2749935;
OH   NCBI_TaxID=4460; Colocasia esculenta (Wild taro) (Arum esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15659770; DOI=10.1099/vir.0.80591-0;
RA   Revill P., Trinh X., Dale J., Harding R.;
RT   "Taro vein chlorosis virus: characterization and variability of a new
RT   nucleorhabdovirus.";
RL   J. Gen. Virol. 86:491-499(2005).
CC   -!- FUNCTION: Attaches the virus to host cellular receptor, inducing
CC       endocytosis of the virion. In the endosome, the acidic pH induces
CC       conformational changes in the glycoprotein trimer, which trigger fusion
CC       between virus and cell membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. Interacts with matrix protein (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass type I
CC       membrane protein {ECO:0000250}.
CC   -!- PTM: Glycosylated by host. Glycosylation is crucial for glycoprotein
CC       export at the cell surface (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nucleorhabdovirus glycoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; AY674964; AAV92086.1; -; Genomic_RNA.
DR   RefSeq; YP_224082.1; NC_006942.1.
DR   GeneID; 5076499; -.
DR   KEGG; vg:5076499; -.
DR   Proteomes; UP000007540; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Glycoprotein; Host-virus interaction; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix; Viral attachment to host cell;
KW   Viral envelope protein; Virion; Virus entry into host cell.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..588
FT                   /note="Glycoprotein"
FT                   /id="PRO_0000299237"
FT   TOPO_DOM        23..547
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        548..568
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        569..588
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   588 AA;  65638 MW;  EC2EE5BCB6F9C43B CRC64;
     MSILVIILIL PILFGEVPPV NSGRVVDLNR NVRTDDHPTD LYPLYECGKQ DTAVPISSWY
     GACRGSCSIT RNTTDNTMEI FFRNDSVGWI DVLSLQTSPI RKNSHVTWYG ECEKSSDVSS
     ARPAPSEIID TVAPAILDKM DTWPYGGAVF IYDTIDFPEC KYTSDYSRSG WRIMVSKRSL
     ELKSDISGEG YIIDPDLGFY FPISKGKGLG RFWWIWQQNS LSQQGCYFKT AGVVNCTLLL
     DTYTYSCPGI NVAFSARIGN HLTSSCVGEV NISTDGITYK LHNQVSVGSI SNQLISLWHQ
     SEEALIQQLI IVINDALGKI ESSYCESTCD LTEIAMSKHS DHPLVIETPV GPWLPASKGG
     EFVVIPCQSE PNLVVMTPIE TCLSPFLIKV KSLKTGEVYW WMPTESHVSP DRQCLGHEEE
     ELYLKSTQRK PLQFEFWKGA YIIDYPYNGS GRWIMNPGGF IHRSSKWFPS LTELSYTAPI
     SLPTITEGVD KKVHQVIMSV GDIGNTTGSX WFAWMQPLGD KLARAVGSVA SSLLIWWTTL
     EEEVKHGVII VFFTVIGLII AVPTLKMLLK GRRPYEPVKS PVVWGGPR