ID   GLYLB_HUMAN             Reviewed;         302 AA.
AC   A0A0U1RQE8;
DT   20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT   17-FEB-2016, sequence version 1.
DT   03-AUG-2022, entry version 34.
DE   RecName: Full=Putative glycine N-acyltransferase-like protein 1B {ECO:0000305};
DE            EC=2.3.1.68 {ECO:0000250|UniProtKB:Q969I3};
GN   Name=GLYATL1B {ECO:0000312|HGNC:HGNC:37865};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
CC   -!- FUNCTION: Putative acyltransferase which transfers an acyl group to the
CC       N-terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor.
CC       {ECO:0000250|UniProtKB:Q969I3}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA +
CC         H(+); Xref=Rhea:RHEA:18469, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:58342, ChEBI:CHEBI:58359, ChEBI:CHEBI:87584; EC=2.3.1.68;
CC         Evidence={ECO:0000250|UniProtKB:Q969I3};
CC   -!- SIMILARITY: Belongs to the glycine N-acyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; AP001258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS86204.1; -.
DR   AlphaFoldDB; A0A0U1RQE8; -.
DR   SMR; A0A0U1RQE8; -.
DR   BioMuta; GLYATL1B; -.
DR   MassIVE; A0A0U1RQE8; -.
DR   PeptideAtlas; A0A0U1RQE8; -.
DR   Ensembl; ENST00000527482.2; ENSP00000488958.1; ENSG00000255151.2.
DR   MANE-Select; ENST00000527482.2; ENSP00000488958.1; NM_001355566.1; NP_001342495.1.
DR   GeneCards; GLYATL1B; -.
DR   HGNC; HGNC:37865; GLYATL1B.
DR   HPA; ENSG00000255151; Group enriched (breast, lymphoid tissue).
DR   neXtProt; NX_A0A0U1RQE8; -.
DR   OpenTargets; ENSG00000255151; -.
DR   VEuPathDB; HostDB:ENSG00000255151; -.
DR   GeneTree; ENSGT00950000183133; -.
DR   OMA; ALVDKFW; -.
DR   Pharos; A0A0U1RQE8; Tdark.
DR   PRO; PR:A0A0U1RQE8; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   RNAct; A0A0U1RQE8; protein.
DR   Bgee; ENSG00000255151; Expressed in vermiform appendix and 13 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IEA:InterPro.
DR   GO; GO:0047946; F:glutamine N-acyltransferase activity; IBA:GO_Central.
DR   GO; GO:0047961; F:glycine N-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0016410; F:N-acyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006541; P:glutamine metabolic process; IBA:GO_Central.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR010313; Glycine_N-acyltransferase.
DR   InterPro; IPR013652; Glycine_N-acyltransferase_C.
DR   InterPro; IPR015938; Glycine_N-acyltransferase_N.
DR   PANTHER; PTHR15298; PTHR15298; 1.
DR   Pfam; PF08444; Gly_acyl_tr_C; 1.
DR   Pfam; PF06021; Gly_acyl_tr_N; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..302
FT                   /note="Putative glycine N-acyltransferase-like protein 1B"
FT                   /id="PRO_0000444477"
SQ   SEQUENCE   302 AA;  34553 MW;  FFEF9FC972F9EB3F CRC64;
     MILLNNSERL LALFKSLARS IPESLKVYGS LFHINHGNPF NMEVLVDSWP EYQMVIIRPQ
     KQEMTDDMDS YTNVYRVFSK DPQKSQEVLK NSEIINWKQK LQIQGFQESL GEGIRAAAFS
     NSVKVEHSRA LLFVTEDILK LYATNKSKLG SWAETGHPDD ELESETPNFK YAQLNVSYSG
     LVNDNWKLGM NKRSLRYIKR CLGALPAACM LGPEGVPVSW VTMDPSCEIG MGYSVEKYRR
     RGNGTRLIMR CMKYLCQKNI PFYGSVLEEN QGVIRKTSAL GFLEASCQWH QWNCYPQNLV
     PL