ID   AMP1_COCNU              Reviewed;           9 AA.
AC   P86705;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 1.
DT   02-JUN-2021, entry version 14.
DE   RecName: Full=Antimicrobial peptide 1 {ECO:0000303|PubMed:19111587};
DE            Short=Cn-AMP1 {ECO:0000303|PubMed:19111587};
OS   Cocos nucifera (Coconut palm).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Arecaceae; Arecoideae; Cocoseae;
OC   Attaleinae; Cocos.
OX   NCBI_TaxID=13894;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TISSUE
RP   SPECIFICITY, AND MASS SPECTROMETRY.
RC   TISSUE=Endosperm {ECO:0000269|PubMed:19111587};
RX   PubMed=19111587; DOI=10.1016/j.peptides.2008.12.001;
RA   Mandal S.M., Dey S., Mandal M., Sarkar S., Maria-Neto S., Franco O.L.;
RT   "Identification and structural insights of three novel antimicrobial
RT   peptides isolated from green coconut water.";
RL   Peptides 30:633-637(2009).
CC   -!- FUNCTION: Has antimicrobial activity against Gram-positive bacteria
CC       B.subtilis (MIC=76 ug/ml) and S.aureus (MIC=80 ug/ml), and against
CC       Gram-negative bacteria E.coli (MIC=82 ug/ml) and P.aeruginosa (MIC=79
CC       ug/ml). {ECO:0000269|PubMed:19111587}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:19111587}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space
CC       {ECO:0000269|PubMed:19111587}.
CC   -!- TISSUE SPECIFICITY: Found in the liquid endosperm contained in green
CC       fruit of coconut palms, also known as coconut water (at protein level).
CC       {ECO:0000269|PubMed:19111587}.
CC   -!- MASS SPECTROMETRY: Mass=858; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:19111587};
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DR   PDB; 2N0V; NMR; -; A=1-9.
DR   PDBsum; 2N0V; -.
DR   BMRB; P86705; -.
DR   GO; GO:0005615; C:extracellular space; IDA:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IDA:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   3D-structure; Antimicrobial; Direct protein sequencing; Plant defense;
KW   Secreted.
FT   PEPTIDE         1..9
FT                   /note="Antimicrobial peptide 1"
FT                   /evidence="ECO:0000269|PubMed:19111587"
FT                   /id="PRO_0000399051"
FT   HELIX           2..4
FT                   /evidence="ECO:0007829|PDB:2N0V"
FT   TURN            5..8
FT                   /evidence="ECO:0007829|PDB:2N0V"
SQ   SEQUENCE   9 AA;  876 MW;  CE4766DDC4087DC2 CRC64;
     SVAGRAQGM