ID   GLYTR_MYCTO             Reviewed;         342 AA.
AC   P9WMX4; L0T716; P71781; Q7D8C9;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Putative glycosyltransferases;
DE            EC=2.4.-.-;
GN   Name=pimF; OrderedLocusNames=MT1549;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: May play only a redundant role in maintaining cell wall
CC       viability and bacterial virulence. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45815.1; -; Genomic_DNA.
DR   PIR; G70712; G70712.
DR   RefSeq; WP_003407612.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMX4; -.
DR   SMR; P9WMX4; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; AAK45815; AAK45815; MT1549.
DR   GeneID; 45425480; -.
DR   KEGG; mtc:MT1549; -.
DR   PATRIC; fig|83331.31.peg.1666; -.
DR   HOGENOM; CLU_033536_0_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Glycosyltransferase; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..342
FT                   /note="Putative glycosyltransferases"
FT                   /id="PRO_0000427226"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   342 AA;  38095 MW;  69373418DD844255 CRC64;
     MRLSIVTTMY MSEPYVLEFY RRARAAADKI TPDVEIIFVD DGSPDAALQQ AVSLLDSDPC
     VRVIQLSRNF GHHKAMMTGL AHATGDLVFL IDSDLEEDPA LLEPFYEKLI STGADVVFGC
     HARRPGGWLR NFGPKIHYRA SALLCDPPLH ENTLTVRLMT ADYVRSLVQH QERELSIAGL
     WQITGFYQVP MSVNKAWKGT TTYTFRRKVA TLVDNVTSFS NKPLVFIFYL GAAIFIISSS
     AAGYLIIDRI FFRALQAGWA SVIVSIWMLG GVTIFCIGLV GIYVSKVFIE TKQRPYTIIR
     RIYGSDLTTR EPSSLKTAFP AAHLSNGKRV TSEPEGLATG NR