ID   GMFG_BOVIN              Reviewed;         142 AA.
AC   Q56JZ9;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Glia maturation factor gamma;
DE            Short=GMF-gamma;
GN   Name=GMFG;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lymphoid epithelium;
RA   Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT   "Analysis of sequences obtained from constructed full-length bovine cDNA
RT   libraries.";
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Kidney;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the actin-binding proteins ADF family. GMF
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AY911328; AAW82096.1; -; mRNA.
DR   EMBL; BC103101; AAI03102.1; -; mRNA.
DR   RefSeq; NP_001019708.1; NM_001024537.2.
DR   AlphaFoldDB; Q56JZ9; -.
DR   SMR; Q56JZ9; -.
DR   STRING; 9913.ENSBTAP00000007090; -.
DR   PaxDb; Q56JZ9; -.
DR   PeptideAtlas; Q56JZ9; -.
DR   PRIDE; Q56JZ9; -.
DR   Ensembl; ENSBTAT00000007090; ENSBTAP00000007090; ENSBTAG00000005390.
DR   GeneID; 514407; -.
DR   KEGG; bta:514407; -.
DR   CTD; 9535; -.
DR   VEuPathDB; HostDB:ENSBTAG00000005390; -.
DR   VGNC; VGNC:29435; GMFG.
DR   eggNOG; KOG1736; Eukaryota.
DR   GeneTree; ENSGT00390000008920; -.
DR   HOGENOM; CLU_087056_1_0_1; -.
DR   InParanoid; Q56JZ9; -.
DR   OMA; EWKMLYA; -.
DR   OrthoDB; 1477747at2759; -.
DR   TreeFam; TF315147; -.
DR   Proteomes; UP000009136; Chromosome 18.
DR   Bgee; ENSBTAG00000005390; Expressed in blood and 106 other tissues.
DR   ExpressionAtlas; Q56JZ9; baseline and differential.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0071933; F:Arp2/3 complex binding; IBA:GO_Central.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0071846; P:actin filament debranching; IBA:GO_Central.
DR   GO; GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; IBA:GO_Central.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; IEA:InterPro.
DR   CDD; cd11283; ADF_GMF-beta_like; 1.
DR   Gene3D; 3.40.20.10; -; 1.
DR   InterPro; IPR002108; ADF-H.
DR   InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR   InterPro; IPR011171; GMF.
DR   InterPro; IPR030076; GMFG.
DR   PANTHER; PTHR11249; PTHR11249; 1.
DR   PANTHER; PTHR11249:SF4; PTHR11249:SF4; 1.
DR   Pfam; PF00241; Cofilin_ADF; 1.
DR   PIRSF; PIRSF001788; GMF-beta; 1.
DR   SMART; SM00102; ADF; 1.
DR   PROSITE; PS51263; ADF_H; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Growth factor; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:O60234"
FT   CHAIN           2..142
FT                   /note="Glia maturation factor gamma"
FT                   /id="PRO_0000231003"
FT   DOMAIN          4..139
FT                   /note="ADF-H"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00599"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:O60234"
SQ   SEQUENCE   142 AA;  16770 MW;  A66CEB46E25320E2 CRC64;
     MSDSLVVCEV DPELKEKLRK FRFRKETDNA AIVMKVDKDR QMVVLEEEFQ NISPEELKME
     LPERQPRFVV YSYKYVHADG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNR LVQTAELTKV
     FEIRTTDDLT EAWLKEKLSF FR