ID   GMH2_SCHPO              Reviewed;         346 AA.
AC   Q09681;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 125.
DE   RecName: Full=Probable alpha-1,2-galactosyltransferase gmh2;
DE            EC=2.4.1.-;
GN   Name=gmh2; ORFNames=SPAC5H10.13c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-
CC       pass type II membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 34 family.
CC       {ECO:0000305}.
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DR   EMBL; CU329670; CAA89963.1; -; Genomic_DNA.
DR   PIR; T38977; S55491.
DR   RefSeq; NP_592826.1; NM_001018226.2.
DR   AlphaFoldDB; Q09681; -.
DR   SMR; Q09681; -.
DR   BioGRID; 278700; 44.
DR   STRING; 4896.SPAC5H10.13c.1; -.
DR   CAZy; GT34; Glycosyltransferase Family 34.
DR   MaxQB; Q09681; -.
DR   PaxDb; Q09681; -.
DR   EnsemblFungi; SPAC5H10.13c.1; SPAC5H10.13c.1:pep; SPAC5H10.13c.
DR   GeneID; 2542227; -.
DR   KEGG; spo:SPAC5H10.13c; -.
DR   PomBase; SPAC5H10.13c; gmh2.
DR   VEuPathDB; FungiDB:SPAC5H10.13c; -.
DR   eggNOG; KOG4748; Eukaryota.
DR   HOGENOM; CLU_021434_2_0_1; -.
DR   InParanoid; Q09681; -.
DR   OMA; ENREEYC; -.
DR   PhylomeDB; Q09681; -.
DR   PRO; PR:Q09681; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0000139; C:Golgi membrane; ISS:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031278; F:alpha-1,2-galactosyltransferase activity; EXP:PomBase.
DR   GO; GO:0006491; P:N-glycan processing; IMP:PomBase.
DR   GO; GO:0006487; P:protein N-linked glycosylation; EXP:PomBase.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR008630; Glyco_trans_34.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR31306; PTHR31306; 1.
DR   Pfam; PF05637; Glyco_transf_34; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane;
KW   Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..346
FT                   /note="Probable alpha-1,2-galactosyltransferase gmh2"
FT                   /id="PRO_0000215167"
FT   TOPO_DOM        1..11
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        12..32
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..346
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        64
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        142
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        224
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   346 AA;  39108 MW;  1AD26CCDFABC0D3E CRC64;
     MALMLSRIPR RFFFLFLTVG LIAGAFLYSL IYFVDVDLVS KVNQLYDQQI APMLSDAIGT
     PSVNHSFELA PLDSHLVATS TTFHEASYES EPQQNPASQN IVLLLVSDGH TSYNNGANTF
     EEAIQNRVDY STKQNYNFEY VNVTGLPIPA VWSKMPAVLQ TMKKYPKAEW IWLLDQDAII
     TNTHLSLQDS FLKPENLQKT LITNTILTKR PINANGDLRY TPSNYSLKDI ENLMVIISQD
     HNGLNAGSIL FRNSPATALF LDIWTDPVVA ECAKANNEQD MLGYLISKHS QLASLVGLIP
     QRKINAFHEG PENMEWQKGD LVIHFAGCWV ENRCDELWQK FYALID