ID   AMP2_SESIN              Reviewed;          99 AA.
AC   B3EWE9;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   25-MAY-2022, entry version 15.
DE   RecName: Full=Antimicrobial protein 2 {ECO:0000303|PubMed:21691771};
DE            Short=Si-AMP2 {ECO:0000303|PubMed:21691771};
DE   Flags: Fragments;
OS   Sesamum indicum (Oriental sesame) (Sesamum orientale).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Pedaliaceae; Sesamum.
OX   NCBI_TaxID=4182;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, AND MASS SPECTROMETRY.
RC   STRAIN=cv. Guatemala {ECO:0000269|PubMed:21691771};
RC   TISSUE=Seed {ECO:0000269|PubMed:21691771};
RX   PubMed=21691771; DOI=10.1007/s10930-011-9337-x;
RA   Maria-Neto S., Honorato R.V., Costa F.T., Almeida R.G., Amaro D.S.,
RA   Oliveira J.T., Vasconcelos I.M., Franco O.L.;
RT   "Bactericidal activity identified in 2S Albumin from sesame seeds and in
RT   silico studies of structure-function relations.";
RL   Protein J. 30:340-350(2011).
CC   -!- FUNCTION: Has antibacterial activity against Gram-negative Klebsiella
CC       sp. but not against E.coli, Proteus sp., Salmonella sp. and Xanthomonas
CC       sp. or against Gram-positive bacteria S.pyogenes, S.aureus and
CC       Rathayibacter sp. Has no antifungal activity.
CC       {ECO:0000269|PubMed:21691771}.
CC   -!- SUBUNIT: Heterodimer. {ECO:0000269|PubMed:21691771}.
CC   -!- MASS SPECTROMETRY: Mass=5874; Method=MALDI; Note=Small subunit.;
CC       Evidence={ECO:0000269|PubMed:21691771};
CC   -!- MASS SPECTROMETRY: Mass=8374; Method=MALDI; Note=Large subunit.;
CC       Evidence={ECO:0000269|PubMed:21691771};
CC   -!- SIMILARITY: Belongs to the 2S seed storage albumins family.
CC       {ECO:0000255}.
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DR   AlphaFoldDB; B3EWE9; -.
DR   SMR; B3EWE9; -.
DR   Proteomes; UP000504604; Genome assembly.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Reference proteome.
FT   CHAIN           <1..>99
FT                   /note="Antimicrobial protein 2"
FT                   /id="PRO_0000415955"
FT   NON_CONS        57..58
FT                   /evidence="ECO:0000303|PubMed:21691771"
FT   NON_TER         1
FT                   /evidence="ECO:0000303|PubMed:21691771"
FT   NON_TER         99
FT                   /evidence="ECO:0000303|PubMed:21691771"
SQ   SEQUENCE   99 AA;  12268 MW;  6509798933D6162D CRC64;
     QEGCEWESRP CNRGCWLPRQ WESVHMRFGV LVLWRAPQFE HFRECCNELR CEALRCMMRM
     RMEYWPRGLQ DQQVYQRARD LEPRKHCGMS YPVECRMPR