GMT_MAGO7
ID GMT_MAGO7 Reviewed; 394 AA.
AC A4RM13; G4MV59;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=GDP-mannose transporter;
DE Short=GMT;
GN Name=VRG4; ORFNames=MGG_08858;
OS Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS fungus) (Pyricularia oryzae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX NCBI_TaxID=242507;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX PubMed=15846337; DOI=10.1038/nature03449;
RA Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL Nature 434:980-986(2005).
CC -!- FUNCTION: Involved in the import of GDP-mannose from the cytoplasm into
CC the Golgi lumen. {ECO:0000250}.
CC -!- SUBUNIT: Homooligomer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane
CC {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic
CC reticulum membrane {ECO:0000250}; Multi-pass membrane protein
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TPT transporter family. SLC35D subfamily.
CC {ECO:0000305}.
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DR EMBL; CM001232; EHA54074.1; -; Genomic_DNA.
DR RefSeq; XP_003713881.1; XM_003713833.1.
DR AlphaFoldDB; A4RM13; -.
DR SMR; A4RM13; -.
DR STRING; 318829.MGG_08858T0; -.
DR EnsemblFungi; MGG_08858T0; MGG_08858T0; MGG_08858.
DR GeneID; 2679844; -.
DR KEGG; mgr:MGG_08858; -.
DR VEuPathDB; FungiDB:MGG_08858; -.
DR eggNOG; KOG1444; Eukaryota.
DR HOGENOM; CLU_025360_1_2_1; -.
DR InParanoid; A4RM13; -.
DR OMA; IRVWIPV; -.
DR OrthoDB; 1093260at2759; -.
DR Proteomes; UP000009058; Chromosome 2.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005458; F:GDP-mannose transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR038736; Vrg4-like.
DR PANTHER; PTHR11132:SF251; PTHR11132:SF251; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle; Endoplasmic reticulum; Golgi apparatus; Membrane;
KW Reference proteome; Sugar transport; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..394
FT /note="GDP-mannose transporter"
FT /id="PRO_0000333526"
FT TOPO_DOM 1..55
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 77..80
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 102..121
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 145..149
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 168..173
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 174..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 199..213
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 235..246
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 268..287
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 309..316
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 317..339
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 340..342
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 363..394
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT REGION 371..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 42381 MW; 5B5712DB20D364D9 CRC64;
MADKKNEDFV VRMPDNGTVE KEPFLARSPP ARARTGSGGG FGDSFSLARV ANNPPAAILA
YCLSSISMTV VNKYVVSGSE WNLNFFYLAV QAIVCIIAIL FCKQIGIITN LAPFDNVKAK
KWFPVSLLLV GMIYTSTKAL QFLSVPVYTI FKNLTIIAIA YGEVLWFGGS VSPLALVSFG
LMVLSSVVAA WADIQSAIHG GSHPSEASTA ISTLNAGYAW MGMNVFCSAA YLLGMRKVIH
KMNFKDWDSM FYNNLLTIPV LIVCSLIAED WSAANLARNF PIESRNALFI GMIYSGLGAI
FISYCSAWCI RVTTSTTYSM VGALNKLPIA ISGLVFFSAP VTFGSVSAIV IGFISGIVYA
WAKARQSSQA KSALPTQQPV MSASSQSNKD ASNS
