ID   GNT13_DICDI             Reviewed;         635 AA.
AC   Q54SH2;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Glycosyltransferase-like protein gnt13;
GN   Name=gnt13; ORFNames=DDB_G0282469;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE.
RX   PubMed=17588537; DOI=10.1016/j.bbrc.2007.06.016;
RA   Pang T.L., Wu C.J., Chen P.A., Weng Y.L., Chen M.Y.;
RT   "Dictyostelium gnt15 encodes a protein with similarity to LARGE and plays
RT   an essential role in development.";
RL   Biochem. Biophys. Res. Commun. 360:83-89(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed at a relatively steady level during
CC       vegetative growth and development. {ECO:0000269|PubMed:17588537}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. Highly
CC       divergent. {ECO:0000305}.
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DR   EMBL; AAFI02000047; EAL66094.1; -; Genomic_DNA.
DR   RefSeq; XP_640067.1; XM_634975.1.
DR   AlphaFoldDB; Q54SH2; -.
DR   STRING; 44689.DDB0231851; -.
DR   PaxDb; Q54SH2; -.
DR   PRIDE; Q54SH2; -.
DR   EnsemblProtists; EAL66094; EAL66094; DDB_G0282469.
DR   GeneID; 8623596; -.
DR   KEGG; ddi:DDB_G0282469; -.
DR   dictyBase; DDB_G0282469; gnt13.
DR   eggNOG; KOG3765; Eukaryota.
DR   HOGENOM; CLU_528327_0_0_1; -.
DR   InParanoid; Q54SH2; -.
DR   PhylomeDB; Q54SH2; -.
DR   PRO; PR:Q54SH2; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0042285; F:xylosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0035269; P:protein O-linked mannosylation; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..635
FT                   /note="Glycosyltransferase-like protein gnt13"
FT                   /id="PRO_0000393408"
FT   TOPO_DOM        1..18
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        19..38
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        39..635
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   REGION          300..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          389..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        41
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        393
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        535
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   635 AA;  73802 MW;  FF5A39DF286A8E3D CRC64;
     MNINTLIINF NKVKRMKNFL ILTLLVVMVV VFLQGPTLMI NNSGQGMGHN VEKIKLEPHV
     KIQRENLERK KIPPKQDFTD GLHASFTTIP FYYKANGIIN QNTNKLYRNY QITIVTQTTV
     DRLSKVSMMA EKWKAPLSVA VFIKDSENPK AEIEKLEKHI ENDYPALSYY SDIHILISNK
     TRYPVNNLRN LAIEHSRTDL VFIMDADFLP PLGLHDYILS QKYYFNIKPS NQHYFKNNLL
     NFYHKKPLNN NDNNNDYNNN PSKIPYDQII DYSTNINTDS EFNNINYNME NLNENEYLKN
     INNNNNNNDN NYNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNIDNN
     IDNKIDNIDN NIDNNNNIDN INNNNNINNI DNNNSNYNDN NNNNNNNNNN NNNNNNNNNN
     NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNEPLK VAFVIPSFSS HIPPSQHPNN
     KMDMIDLVKS SKIEPSNSRV CKKCHSPTNF EKWMDAVEPY EVEYKWIFEP YLVFNKTQNI
     PFDERLKGYG FDKNSHAFSM AVEGFHFVVL PDSFIIHVNH SPSTWEGPSL DEQQWDALRV
     VCEIIPDVKI KNGYNPNVVL FNEPLPNECF SDHHW