ID   GNTK_RAT                Reviewed;         185 AA.
AC   Q32PY9;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Probable gluconokinase;
DE            EC=2.7.1.12;
DE   AltName: Full=Gluconate kinase;
GN   Name=Idnk;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+);
CC         Xref=Rhea:RHEA:19433, ChEBI:CHEBI:15378, ChEBI:CHEBI:18391,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58759, ChEBI:CHEBI:456216;
CC         EC=2.7.1.12;
CC   -!- PATHWAY: Carbohydrate acid metabolism; D-gluconate degradation.
CC   -!- SIMILARITY: Belongs to the gluconokinase GntK/GntV family.
CC       {ECO:0000305}.
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DR   EMBL; BC107923; AAI07924.1; -; mRNA.
DR   RefSeq; NP_001032439.1; NM_001037362.1.
DR   AlphaFoldDB; Q32PY9; -.
DR   SMR; Q32PY9; -.
DR   STRING; 10116.ENSRNOP00000026407; -.
DR   PaxDb; Q32PY9; -.
DR   Ensembl; ENSRNOT00000116956; ENSRNOP00000082724; ENSRNOG00000019519.
DR   GeneID; 498695; -.
DR   KEGG; rno:498695; -.
DR   UCSC; RGD:1564546; rat.
DR   CTD; 414328; -.
DR   RGD; 1564546; Idnk.
DR   eggNOG; KOG3354; Eukaryota.
DR   GeneTree; ENSGT00390000003364; -.
DR   HOGENOM; CLU_077168_4_1_1; -.
DR   InParanoid; Q32PY9; -.
DR   OMA; ENFIQVS; -.
DR   OrthoDB; 1275465at2759; -.
DR   PhylomeDB; Q32PY9; -.
DR   TreeFam; TF315136; -.
DR   UniPathway; UPA00792; -.
DR   PRO; PR:Q32PY9; -.
DR   Proteomes; UP000002494; Chromosome 17.
DR   Bgee; ENSRNOG00000019519; Expressed in kidney and 19 other tissues.
DR   Genevisible; Q32PY9; RN.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046316; F:gluconokinase activity; IBA:GO_Central.
DR   GO; GO:0046177; P:D-gluconate catabolic process; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd02021; GntK; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR031322; Shikimate/glucono_kinase.
DR   InterPro; IPR006001; Therm_gnt_kin.
DR   PANTHER; PTHR43442; PTHR43442; 1.
DR   Pfam; PF01202; SKI; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01313; therm_gnt_kin; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Kinase; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..185
FT                   /note="Probable gluconokinase"
FT                   /id="PRO_0000327372"
FT   BINDING         11..18
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   185 AA;  20210 MW;  4B2EFBD558A1AD3C CRC64;
     METPGVLLVM GVSGSGKSTV GALLANKLGW KFYDADDYHS EENRIKMGKG VPLNDQDRIP
     WLCSLHDILL RDVASGQSVV LACSALKKMY RDILNRGGSD VPPRSDESAK EEPLAGGKFL
     VVHLCGSFEL IYGRLLQRRG HFMPPELLQS QFSILEPPSA PENFIHISVD KGLPEIAAAV
     LEALK