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GNTK_XENTR
ID   GNTK_XENTR              Reviewed;         190 AA.
AC   B0BML1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Probable gluconokinase;
DE            EC=2.7.1.12;
DE   AltName: Full=Gluconate kinase;
GN   Name=idnk;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+);
CC         Xref=Rhea:RHEA:19433, ChEBI:CHEBI:15378, ChEBI:CHEBI:18391,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58759, ChEBI:CHEBI:456216;
CC         EC=2.7.1.12;
CC   -!- PATHWAY: Carbohydrate acid metabolism; D-gluconate degradation.
CC   -!- SIMILARITY: Belongs to the gluconokinase GntK/GntV family.
CC       {ECO:0000305}.
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DR   EMBL; BC158476; AAI58477.1; -; mRNA.
DR   RefSeq; NP_001120064.1; NM_001126592.1.
DR   AlphaFoldDB; B0BML1; -.
DR   SMR; B0BML1; -.
DR   STRING; 8364.ENSXETP00000057500; -.
DR   PaxDb; B0BML1; -.
DR   GeneID; 100145063; -.
DR   KEGG; xtr:100145063; -.
DR   CTD; 414328; -.
DR   eggNOG; KOG3354; Eukaryota.
DR   HOGENOM; CLU_077168_4_1_1; -.
DR   InParanoid; B0BML1; -.
DR   OrthoDB; 1275465at2759; -.
DR   UniPathway; UPA00792; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046316; F:gluconokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046177; P:D-gluconate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd02021; GntK; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR031322; Shikimate/glucono_kinase.
DR   InterPro; IPR006001; Therm_gnt_kin.
DR   PANTHER; PTHR43442; PTHR43442; 1.
DR   Pfam; PF01202; SKI; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01313; therm_gnt_kin; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Kinase; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..190
FT                   /note="Probable gluconokinase"
FT                   /id="PRO_0000327373"
FT   BINDING         7..14
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   190 AA;  21540 MW;  83600D6F4B8DC010 CRC64;
     MIIVIMGVSG SGKTVVGSQL AKKLGWNFYD ADDYHPLENK EKMSQGTPLN DQDRHPWLCE
     LHEIMMREKA LGQHVVLACS ALKRAYRSTL LTGSTPHWPE NYQENDDLSS DTLFVHLHGS
     LEILSRRLLE RKGHFMPRTL LDSQIDTLEP PSAPERFIAI DVDKDISVIV SEIEGEVDRK
     MMLVKSAQKD
 
 
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