ID   GNTR_BACLI              Reviewed;         243 AA.
AC   P46833;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Gluconate operon transcriptional repressor;
DE   AltName: Full=P28 protein;
GN   Name=gntR;
OS   Bacillus licheniformis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1402;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BGSC5A2;
RX   PubMed=8535972; DOI=10.1093/dnares/1.4.157;
RA   Yoshida K., Seki S., Fujita Y.;
RT   "Nucleotide sequence and features of the Bacillus licheniformis gnt
RT   operon.";
RL   DNA Res. 1:157-162(1994).
CC   -!- FUNCTION: Transcriptional repressor of the gluconate operon (gntRKPZ),
CC       which encodes the proteins for gluconate utilization. Represses mRNA
CC       synthesis by binding to the gnt operator; the binding is suppressed by
CC       gluconate or glucono-delta-lactone.
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DR   EMBL; D31631; BAA06501.1; -; Genomic_DNA.
DR   PIR; JC2303; JC2303.
DR   AlphaFoldDB; P46833; -.
DR   SMR; P46833; -.
DR   PATRIC; fig|1402.64.peg.2235; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.20.120.530; -; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF48008; SSF48008; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding; Gluconate utilization; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..243
FT                   /note="Gluconate operon transcriptional repressor"
FT                   /id="PRO_0000050647"
FT   DOMAIN          17..83
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        44..63
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   243 AA;  28208 MW;  563BBE4D61E37759 CRC64;
     MSQSKNLLYP EKWLSRASTG VRVACELRMR IISGLIESGT ILSENKLAAE FSVSRSPIRE
     ALKILASEKI IRLERMGAVV IGLTEKEIGE IYDVRLVMET FVFERLGRAN VDELVTDLSK
     ILEMMKVSIK YKDADEFSFQ DVLFHETIVR SINHSYILMI WNNLKPVMES FILLSMRARL
     KEKYEDFERI LDNHELYIKA IKTKDRDLML KSLHQNFDDV QGKVEDLWLS QQMLAKGAEQ
     END