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GNUT_PSEAE
ID   GNUT_PSEAE              Reviewed;         450 AA.
AC   Q9ZIJ1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Gluconate permease;
GN   Name=gnuT; OrderedLocusNames=PA2322;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RA   Hager P.W., Covert-Rinaldi A., Wallace W.H., Phibbs P.V. Jr.;
RT   "Cloning and sequence analysis of the gluconate operon of Pseudomonas
RT   aeruginosa PAO.";
RL   Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- PATHWAY: Carbohydrate acid metabolism; D-gluconate degradation.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GntP permease family. {ECO:0000305}.
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DR   EMBL; AF026470; AAD01803.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG05710.1; -; Genomic_DNA.
DR   PIR; E83355; E83355.
DR   RefSeq; NP_251012.1; NC_002516.2.
DR   RefSeq; WP_003107128.1; NZ_QZGE01000021.1.
DR   AlphaFoldDB; Q9ZIJ1; -.
DR   STRING; 287.DR97_6111; -.
DR   PaxDb; Q9ZIJ1; -.
DR   PRIDE; Q9ZIJ1; -.
DR   DNASU; 883019; -.
DR   EnsemblBacteria; AAG05710; AAG05710; PA2322.
DR   GeneID; 883019; -.
DR   KEGG; pae:PA2322; -.
DR   PATRIC; fig|208964.12.peg.2427; -.
DR   PseudoCAP; PA2322; -.
DR   HOGENOM; CLU_027949_0_2_6; -.
DR   InParanoid; Q9ZIJ1; -.
DR   OMA; LMRIGIP; -.
DR   PhylomeDB; Q9ZIJ1; -.
DR   BioCyc; PAER208964:G1FZ6-2361-MON; -.
DR   UniPathway; UPA00792; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015128; F:gluconate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0046177; P:D-gluconate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0035429; P:gluconate transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR003474; Glcn_transporter.
DR   PANTHER; PTHR30354; PTHR30354; 1.
DR   Pfam; PF02447; GntP_permease; 1.
DR   PIRSF; PIRSF002746; Gluconate_transporter; 1.
DR   TIGRFAMs; TIGR00791; gntP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Gluconate utilization; Membrane;
KW   Reference proteome; Sugar transport; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..450
FT                   /note="Gluconate permease"
FT                   /id="PRO_0000061941"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   450 AA;  47297 MW;  AED12865DBD97436 CRC64;
     MFGMSHDAYL LLDALVTIIG LIVLITRFKV HPFIALIIAA GFLGLTSGMP VEKIVKSFQD
     GFGGVLGFVG VILALGTMLG KLMADSGGAD QIARTLIRAF GKERVHWSMM LAAFLVGIPL
     FFEIGFILLI PLVFIVARRS GVSLIKIGIP LLAGLSAVHG LVPPHPGPLL AIGVFGADIG
     KTILYGLIVA LPTAAIAGPL FGALVSRYIP GTPSAELVEQ IAHEPETQDL PSFGVTLATV
     LLPVFLMLLK TFADVAFPDG HAFRAWMDMI GHPISALLLA LLVALYTFGY ARGFDSKKIL
     RLLDQSLAPT AAIVMIIGAG GGFKQMLVAS GVGDVIGHLA VNAQISPILL AWLVAAVIRI
     ATGSATVATI TGAGIVVPVI DLIPGVNREL LVLATGAGSL ILSHVNDAGF WLVKQYFNMS
     VSETFKTWTA METILSVVGL VFILLLSLVL
 
 
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