GNUT_PSEAE
ID GNUT_PSEAE Reviewed; 450 AA.
AC Q9ZIJ1;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Gluconate permease;
GN Name=gnuT; OrderedLocusNames=PA2322;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RA Hager P.W., Covert-Rinaldi A., Wallace W.H., Phibbs P.V. Jr.;
RT "Cloning and sequence analysis of the gluconate operon of Pseudomonas
RT aeruginosa PAO.";
RL Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- PATHWAY: Carbohydrate acid metabolism; D-gluconate degradation.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GntP permease family. {ECO:0000305}.
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DR EMBL; AF026470; AAD01803.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG05710.1; -; Genomic_DNA.
DR PIR; E83355; E83355.
DR RefSeq; NP_251012.1; NC_002516.2.
DR RefSeq; WP_003107128.1; NZ_QZGE01000021.1.
DR AlphaFoldDB; Q9ZIJ1; -.
DR STRING; 287.DR97_6111; -.
DR PaxDb; Q9ZIJ1; -.
DR PRIDE; Q9ZIJ1; -.
DR DNASU; 883019; -.
DR EnsemblBacteria; AAG05710; AAG05710; PA2322.
DR GeneID; 883019; -.
DR KEGG; pae:PA2322; -.
DR PATRIC; fig|208964.12.peg.2427; -.
DR PseudoCAP; PA2322; -.
DR HOGENOM; CLU_027949_0_2_6; -.
DR InParanoid; Q9ZIJ1; -.
DR OMA; LMRIGIP; -.
DR PhylomeDB; Q9ZIJ1; -.
DR BioCyc; PAER208964:G1FZ6-2361-MON; -.
DR UniPathway; UPA00792; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015128; F:gluconate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0046177; P:D-gluconate catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0035429; P:gluconate transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003474; Glcn_transporter.
DR PANTHER; PTHR30354; PTHR30354; 1.
DR Pfam; PF02447; GntP_permease; 1.
DR PIRSF; PIRSF002746; Gluconate_transporter; 1.
DR TIGRFAMs; TIGR00791; gntP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Gluconate utilization; Membrane;
KW Reference proteome; Sugar transport; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..450
FT /note="Gluconate permease"
FT /id="PRO_0000061941"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 450 AA; 47297 MW; AED12865DBD97436 CRC64;
MFGMSHDAYL LLDALVTIIG LIVLITRFKV HPFIALIIAA GFLGLTSGMP VEKIVKSFQD
GFGGVLGFVG VILALGTMLG KLMADSGGAD QIARTLIRAF GKERVHWSMM LAAFLVGIPL
FFEIGFILLI PLVFIVARRS GVSLIKIGIP LLAGLSAVHG LVPPHPGPLL AIGVFGADIG
KTILYGLIVA LPTAAIAGPL FGALVSRYIP GTPSAELVEQ IAHEPETQDL PSFGVTLATV
LLPVFLMLLK TFADVAFPDG HAFRAWMDMI GHPISALLLA LLVALYTFGY ARGFDSKKIL
RLLDQSLAPT AAIVMIIGAG GGFKQMLVAS GVGDVIGHLA VNAQISPILL AWLVAAVIRI
ATGSATVATI TGAGIVVPVI DLIPGVNREL LVLATGAGSL ILSHVNDAGF WLVKQYFNMS
VSETFKTWTA METILSVVGL VFILLLSLVL