ID   GOG6C_HUMAN             Reviewed;         693 AA.
AC   A6NDK9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Golgin subfamily A member 6C;
GN   Name=GOLGA6C;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA6 family. {ECO:0000305}.
CC   -!- CAUTION: Maps to a duplicated region on chromosome 15; the gene is
CC       present in at least 4 almost identical copies. {ECO:0000305}.
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DR   EMBL; AC068338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS58388.1; -.
DR   RefSeq; NP_001157876.1; NM_001164404.1.
DR   AlphaFoldDB; A6NDK9; -.
DR   SMR; A6NDK9; -.
DR   BioGRID; 575950; 1.
DR   IntAct; A6NDK9; 2.
DR   iPTMnet; A6NDK9; -.
DR   PhosphoSitePlus; A6NDK9; -.
DR   BioMuta; GOLGA6C; -.
DR   EPD; A6NDK9; -.
DR   MassIVE; A6NDK9; -.
DR   PaxDb; A6NDK9; -.
DR   PeptideAtlas; A6NDK9; -.
DR   PRIDE; A6NDK9; -.
DR   ProteomicsDB; 914; -.
DR   DNASU; 653641; -.
DR   Ensembl; ENST00000300576.6; ENSP00000300576.5; ENSG00000167195.8.
DR   GeneID; 653641; -.
DR   KEGG; hsa:653641; -.
DR   MANE-Select; ENST00000300576.6; ENSP00000300576.5; NM_001164404.2; NP_001157876.1.
DR   UCSC; uc002azs.3; human.
DR   CTD; 653641; -.
DR   GeneCards; GOLGA6C; -.
DR   HGNC; HGNC:32206; GOLGA6C.
DR   HPA; ENSG00000167195; Tissue enriched (testis).
DR   neXtProt; NX_A6NDK9; -.
DR   PharmGKB; PA162389919; -.
DR   VEuPathDB; HostDB:ENSG00000167195; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00530000062932; -.
DR   HOGENOM; CLU_012403_1_2_1; -.
DR   InParanoid; A6NDK9; -.
DR   OMA; NSRYHEL; -.
DR   OrthoDB; 358120at2759; -.
DR   PhylomeDB; A6NDK9; -.
DR   TreeFam; TF316990; -.
DR   PathwayCommons; A6NDK9; -.
DR   SignaLink; A6NDK9; -.
DR   BioGRID-ORCS; 653641; 26 hits in 926 CRISPR screens.
DR   GenomeRNAi; 653641; -.
DR   Pharos; A6NDK9; Tdark.
DR   PRO; PR:A6NDK9; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; A6NDK9; protein.
DR   Bgee; ENSG00000167195; Expressed in right testis and 10 other tissues.
DR   Genevisible; A6NDK9; HS.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 2.
DR   Pfam; PF15070; GOLGA2L5; 3.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..693
FT                   /note="Golgin subfamily A member 6C"
FT                   /id="PRO_0000332249"
FT   REGION          20..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          629..693
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          73..611
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        20..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        504..547
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        678..693
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   693 AA;  79884 MW;  BEA09FD2D471FB8D CRC64;
     MWPQPYLPPH PMMLEESRQN KLAAAKKKLK EYQQRKSPGI PAGAKTKKKK TDSSPETTTS
     GGGHSPGDSQ YQELAVALES SSVTINQLNE NIESLKQQKK QVEHQLEEAK KTNNEIHKAQ
     MEQLETINIL TLEKADLKTT LYHTKRAARH FEEESKDLAG RLQYSLQRIQ ELERALSAVS
     TQQQEEDRSS SCREAVLQRR LQQTIKERAL LNAHVTQVTE SLKQVQLERD EYAKHIKGER
     ARWQERMWKM SVEARTLKEE KKRDIHRIQE LERSLSELKN QMAEPPSLAP PAVTSVVEQL
     QDEAKHLRQE VEGLEGKLQS QVENNQALSL LSKEQKQRLQ EQEEMLREQE AQRVREQERL
     CEQNERLREQ QKTLQEQGER LRKQEQRLRK QEERLRKEEE RLQKQEKRLW DQEERLWKKE
     ERLQKQEERL ALSQNHKLDK QLAEPQCSFE DLNNEKKSAL QLEQQVKELQ EKLDEEHLEA
     ASQRNQQLET QLSLVALPGE GDGGQHLDSE EEEAPRPTPN IPEDLESREA TSSFMDLPKE
     KADGTEQVER RELGFVQPSG VTDGMRESFT VYESQGAVPN TRHQEMEDVI RLAQKEEEMK
     VKLLELQELV LPLVGNHEGH GKFLIAAQNP ADEPTPGAPA PQELGAAGEQ DDFYEVSLDN
     NVEPAPGAAR EGSPHDNPPV QQIVQLSPVM QDT