ID   GOG8C_HUMAN             Reviewed;         597 AA.
AC   A6NN73;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Golgin subfamily A member 8C;
GN   Name=GOLGA8CP; Synonyms=GOLGA8C;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000305}.
CC   -!- CAUTION: A family of highly similar proteins (GOLGA8A, GOLGA8B,
CC       GOLGA8C, GOLGA8D, GOLGA8E, GOLGA8F, GOLGA8G) are encoded by a repeated
CC       region on chromosome 15q11-15q13. Our sequences are in agreement with
CC       HGNC nomenclature. {ECO:0000305}.
CC   -!- CAUTION: Defined as a pseudogene by HGNC. However, proteomics data
CC       suggest the existence of the protein. {ECO:0000305}.
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DR   EMBL; AC131280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A6NN73; -.
DR   SMR; A6NN73; -.
DR   IntAct; A6NN73; 1.
DR   BioMuta; HGNC:32375; -.
DR   jPOST; A6NN73; -.
DR   MassIVE; A6NN73; -.
DR   MaxQB; A6NN73; -.
DR   PeptideAtlas; A6NN73; -.
DR   PRIDE; A6NN73; -.
DR   ProteomicsDB; 1585; -.
DR   GeneCards; GOLGA8CP; -.
DR   HGNC; HGNC:32375; GOLGA8CP.
DR   neXtProt; NX_A6NN73; -.
DR   InParanoid; A6NN73; -.
DR   PhylomeDB; A6NN73; -.
DR   PathwayCommons; A6NN73; -.
DR   SignaLink; A6NN73; -.
DR   Pharos; A6NN73; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; A6NN73; protein.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043937; GM130_C.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 2.
DR   Pfam; PF19046; GM130_C; 1.
DR   Pfam; PF15070; GOLGA2L5; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..597
FT                   /note="Golgin subfamily A member 8C"
FT                   /id="PRO_0000332960"
FT   REGION          1..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          96..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          457..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          549..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          81..141
FT                   /evidence="ECO:0000255"
FT   COILED          199..255
FT                   /evidence="ECO:0000255"
FT   COILED          296..394
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..69
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   597 AA;  67128 MW;  F2A5F6ED8ABD4226 CRC64;
     MAEETRQSKL AAAKRKLKEY WQRNSPGVPA GAKRNRKTNG SIHETATSGG CHSPGDSSST
     SSSLHAPQSP CQELAVVPDS RSVKVSQLKN TIKSLKQQKK QVEHQLEEEK KANNEKQKAE
     RGLEVQIQRL NIQKGKLNTD LYHTKRSLRY FEEESKDLAV RLQHSLQRKG ELERALSAVT
     ATQKKKAERF SSRSKARMEW KLEQSMREQA LLKAQLTQLK ESLKEVQLER DEYAEHLKGE
     RARWQQRMRK MSQEVCSLKK EKKHDKYRVE TLERSLSKLK HQMAEPLPPE PPAVPSEVEL
     QHLRKELERV AGALQAQVEY NQRISLLNEG QKERLREQEE RLQEQQERLR EQEERLQQLA
     EPQNSFKELN NENKSVLQLE QQVKELQEKL GKRLAHPVAS AQKEPEAAVP APGPGGESSG
     FMDHLEEKAD LSELVEKEEL GFFQYYRERC HQKVYHPITK PGGSAKDAAP GGGHHQAGPG
     QGGDEGEAAG AAGDGVAAGG DYKGHSKFLV TAQNPAHEPS PGAPAPQELG AAHKHGDLCE
     VSLTDSVEPV QGETREGSPH DKPTAQPIVQ DHQEHPGLGS NCCVPFFCWA WPPRRRR