GOG8D_HUMAN
ID GOG8D_HUMAN Reviewed; 430 AA.
AC Q0D2H9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Putative golgin subfamily A member 8D;
GN Name=GOLGA8DP; Synonyms=GOLGA8D;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q0D2H9; Q6UY14-3: ADAMTSL4; NbExp=3; IntAct=EBI-10181276, EBI-10173507;
CC Q0D2H9; P18848: ATF4; NbExp=3; IntAct=EBI-10181276, EBI-492498;
CC Q0D2H9; Q14032: BAAT; NbExp=3; IntAct=EBI-10181276, EBI-8994378;
CC Q0D2H9; Q00994: BEX3; NbExp=3; IntAct=EBI-10181276, EBI-741753;
CC Q0D2H9; Q99459: CDC5L; NbExp=3; IntAct=EBI-10181276, EBI-374880;
CC Q0D2H9; Q53EZ4: CEP55; NbExp=3; IntAct=EBI-10181276, EBI-747776;
CC Q0D2H9; Q12929: EPS8; NbExp=3; IntAct=EBI-10181276, EBI-375576;
CC Q0D2H9; O14653: GOSR2; NbExp=5; IntAct=EBI-10181276, EBI-4401517;
CC Q0D2H9; Q8N4P3: HDDC3; NbExp=3; IntAct=EBI-10181276, EBI-750003;
CC Q0D2H9; V9HWG0: HEL25; NbExp=3; IntAct=EBI-10181276, EBI-10183977;
CC Q0D2H9; Q8NC69: KCTD6; NbExp=3; IntAct=EBI-10181276, EBI-2511344;
CC Q0D2H9; A1A4E9: KRT13; NbExp=3; IntAct=EBI-10181276, EBI-10171552;
CC Q0D2H9; P60370: KRTAP10-5; NbExp=3; IntAct=EBI-10181276, EBI-10172150;
CC Q0D2H9; P60409: KRTAP10-7; NbExp=3; IntAct=EBI-10181276, EBI-10172290;
CC Q0D2H9; P60410: KRTAP10-8; NbExp=3; IntAct=EBI-10181276, EBI-10171774;
CC Q0D2H9; P50222: MEOX2; NbExp=3; IntAct=EBI-10181276, EBI-748397;
CC Q0D2H9; Q13287: NMI; NbExp=6; IntAct=EBI-10181276, EBI-372942;
CC Q0D2H9; Q08499: PDE4D; NbExp=3; IntAct=EBI-10181276, EBI-1642831;
CC Q0D2H9; Q5VU43: PDE4DIP; NbExp=3; IntAct=EBI-10181276, EBI-1105124;
CC Q0D2H9; Q96R06: SPAG5; NbExp=3; IntAct=EBI-10181276, EBI-413317;
CC Q0D2H9; O75558: STX11; NbExp=3; IntAct=EBI-10181276, EBI-714135;
CC Q0D2H9; P15884: TCF4; NbExp=3; IntAct=EBI-10181276, EBI-533224;
CC Q0D2H9; Q8N6Y0: USHBP1; NbExp=3; IntAct=EBI-10181276, EBI-739895;
CC -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. A family of highly
CC similar proteins (GOLGA8A, GOLGA8B, GOLGA8C, GOLGA8D, GOLGA8E, GOLGA8F,
CC GOLGA8G) are encoded by a repeated region on chromosome 15q11-15q13.
CC Our sequences are in agreement with HGNC nomenclature. {ECO:0000305}.
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DR EMBL; BC110417; AAI10418.1; -; mRNA.
DR AlphaFoldDB; Q0D2H9; -.
DR SMR; Q0D2H9; -.
DR IntAct; Q0D2H9; 24.
DR BioMuta; HGNC:32376; -.
DR DMDM; 121940175; -.
DR jPOST; Q0D2H9; -.
DR MassIVE; Q0D2H9; -.
DR PeptideAtlas; Q0D2H9; -.
DR PRIDE; Q0D2H9; -.
DR GeneCards; GOLGA8DP; -.
DR HGNC; HGNC:32376; GOLGA8DP.
DR neXtProt; NX_Q0D2H9; -.
DR InParanoid; Q0D2H9; -.
DR PhylomeDB; Q0D2H9; -.
DR PathwayCommons; Q0D2H9; -.
DR SignaLink; Q0D2H9; -.
DR Pharos; Q0D2H9; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q0D2H9; protein.
DR GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR InterPro; IPR043937; GM130_C.
DR InterPro; IPR043976; GOLGA_cons_dom.
DR InterPro; IPR024858; Golgin_A.
DR PANTHER; PTHR10881; PTHR10881; 1.
DR Pfam; PF19046; GM130_C; 1.
DR Pfam; PF15070; GOLGA2L5; 2.
PE 5: Uncertain;
KW Coiled coil; Reference proteome.
FT CHAIN 1..430
FT /note="Putative golgin subfamily A member 8D"
FT /id="PRO_0000314966"
FT REGION 138..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2..217
FT /evidence="ECO:0000255"
FT COMPBIAS 223..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 48423 MW; 564494F24DF6DBA1 CRC64;
MEWKLEQSMR EQALLKAQLT QLKESLKEVQ LERDEYAEHL KGERARWQQR MRKMSQEVCS
LKKEKKHDKY RVEKLERSLS KLKNQMAEPL PPEPPAVPSE VELQHLRKEL ERVAGALQAQ
VEYNQRISLL NEGQKERLRE QEERLQEQQE RLPEQEERLQ QLAEPQNSFK ELNNENKSVL
QLEQQVKELQ EKLGKERLEA ASQQKQQLTA QLSLMALPGE GHGGEHLDSE GEEAPRPMPS
VPEDLESREA MSGFMDHLEE KADLSELVEK EELGFFQYYR ERCHQKVYHP ITKPGGSAKD
AAPGGGHHQA GPGQGGDEGE AAGAAGDGVA AGGDYKGHSK FLVTAQNPAH EPSPGAPAPQ
ELGAAHKHGD LCEVSLTDSV EPVQGEAREG SPHDNPTAQP IVQDHQEHPG LGSNCCVPFF
CWAWLPRRRR
