ID   GOG8K_HUMAN             Reviewed;         630 AA.
AC   D6RF30;
DT   09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT   23-FEB-2022, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Golgin subfamily A member 8K;
GN   Name=GOLGA8K {ECO:0000312|HGNC:HGNC:38652};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000255}.
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DR   EMBL; AC139426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS61577.1; -.
DR   AlphaFoldDB; D6RF30; -.
DR   STRING; 9606.ENSP00000426691; -.
DR   iPTMnet; D6RF30; -.
DR   PhosphoSitePlus; D6RF30; -.
DR   BioMuta; GOLGA8K; -.
DR   jPOST; D6RF30; -.
DR   MassIVE; D6RF30; -.
DR   PaxDb; D6RF30; -.
DR   PeptideAtlas; D6RF30; -.
DR   PRIDE; D6RF30; -.
DR   Ensembl; ENST00000512626.3; ENSP00000426691.2; ENSG00000249931.5.
DR   MANE-Select; ENST00000512626.3; ENSP00000426691.2; NM_001282493.2; NP_001269422.1.
DR   UCSC; uc032byu.2; human.
DR   GeneCards; GOLGA8K; -.
DR   HGNC; HGNC:38652; GOLGA8K.
DR   HPA; ENSG00000249931; Tissue enriched (testis).
DR   neXtProt; NX_D6RF30; -.
DR   OpenTargets; ENSG00000249931; -.
DR   VEuPathDB; HostDB:ENSG00000249931; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00530000062932; -.
DR   HOGENOM; CLU_012403_1_2_1; -.
DR   InParanoid; D6RF30; -.
DR   PhylomeDB; D6RF30; -.
DR   Pharos; D6RF30; Tdark.
DR   PRO; PR:D6RF30; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; D6RF30; protein.
DR   Bgee; ENSG00000249931; Expressed in right lobe of thyroid gland and 96 other tissues.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043937; GM130_C.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 1.
DR   Pfam; PF19046; GM130_C; 1.
DR   Pfam; PF15070; GOLGA2L5; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..630
FT                   /note="Golgin subfamily A member 8K"
FT                   /id="PRO_0000420859"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          424..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          86..148
FT                   /evidence="ECO:0000255"
FT   COILED          224..411
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..379
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  71556 MW;  8E4A95125469DEE0 CRC64;
     MAEETQHNKL AAAKKKLKEY WQKNSPRVPA GANRNRKTNG SIPEKATSGG CQPPRDSATG
     FHREGPTSSA TLKDLESPCQ ERAVVLDSRS VEISQLKNTI KSLKQQKKQV EHQLEEEKKA
     NNKKQKAKRV LEVQIQTLNI QKEELNTDLY HMKRSLRYFE EKSKDLAVRL QHSLQRKGEL
     ESVLSNVMAT QKKKANQLSS RSKARTEWKL EQSMREEALL KVQLTQLKES FQQVQLERDE
     YSEHLKGERA RWQQRMRKMS QEICTLKKEK QQDMRRVEKL ERSLSKLKNQ MAEPLPPEPP
     AVPSEVELQH LRKELERVAG ELQAQVKKNQ RISLLNQRQE ERIQEQEERL RKQEERIQEQ
     HKSLQQLAKP QSVFEEPNNE NKNALQLEQQ VKELQEKLGE EHLEAASQQN QQLTAQLSLM
     ALPGEGHGEH LDSEGEEAPQ PMPSVPEDLE SREAMSSFMD HLKEKADLSE LVKKELCFIH
     HWRDRRHQKT HHLLSEPGGC AKDAALGGGH HQAGAQGGDE GEAAGAAADG IAAYSNYNNG
     HRKFLAAAHN PADEPGPGAP APQELGAADK HGDLREVSLT SSAQGEARED PLLDKPTAQP
     IVQDHKEHPG LGSNCCVPLF CWAWLPRRRR