ID   GOG8N_HUMAN             Reviewed;         632 AA.
AC   F8WBI6;
DT   09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Golgin subfamily A member 8N;
GN   Name=GOLGA8N {ECO:0000312|HGNC:HGNC:44405};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000255}.
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DR   EMBL; AC123768; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS61578.1; -.
DR   RefSeq; NP_001269423.1; NM_001282494.1.
DR   AlphaFoldDB; F8WBI6; -.
DR   SMR; F8WBI6; -.
DR   BioGRID; 568980; 1.
DR   iPTMnet; F8WBI6; -.
DR   PhosphoSitePlus; F8WBI6; -.
DR   BioMuta; GOLGA8N; -.
DR   EPD; F8WBI6; -.
DR   jPOST; F8WBI6; -.
DR   MassIVE; F8WBI6; -.
DR   MaxQB; F8WBI6; -.
DR   PaxDb; F8WBI6; -.
DR   PeptideAtlas; F8WBI6; -.
DR   PRIDE; F8WBI6; -.
DR   Antibodypedia; 66964; 10 antibodies from 2 providers.
DR   DNASU; 643699; -.
DR   Ensembl; ENST00000448387.6; ENSP00000398454.2; ENSG00000232653.8.
DR   GeneID; 643699; -.
DR   KEGG; hsa:643699; -.
DR   UCSC; uc021sin.2; human.
DR   CTD; 643699; -.
DR   GeneCards; GOLGA8N; -.
DR   HGNC; HGNC:44405; GOLGA8N.
DR   HPA; ENSG00000232653; Low tissue specificity.
DR   neXtProt; NX_F8WBI6; -.
DR   OpenTargets; ENSG00000232653; -.
DR   VEuPathDB; HostDB:ENSG00000232653; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00530000062932; -.
DR   InParanoid; F8WBI6; -.
DR   OMA; AYSHYNN; -.
DR   PhylomeDB; F8WBI6; -.
DR   PathwayCommons; F8WBI6; -.
DR   SignaLink; F8WBI6; -.
DR   BioGRID-ORCS; 643699; 147 hits in 536 CRISPR screens.
DR   GenomeRNAi; 643699; -.
DR   Pharos; F8WBI6; Tdark.
DR   PRO; PR:F8WBI6; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; F8WBI6; protein.
DR   Bgee; ENSG00000232653; Expressed in sural nerve and 96 other tissues.
DR   ExpressionAtlas; F8WBI6; baseline and differential.
DR   Genevisible; F8WBI6; HS.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043937; GM130_C.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 1.
DR   Pfam; PF19046; GM130_C; 1.
DR   Pfam; PF15070; GOLGA2L5; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..632
FT                   /note="Golgin subfamily A member 8N"
FT                   /id="PRO_0000420861"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          505..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          552..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          85..150
FT                   /evidence="ECO:0000255"
FT   COILED          209..421
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   632 AA;  71524 MW;  75FDDFF0DA3000DB CRC64;
     MAEETQHNKL AAAKKKLKEY WQKNRPRVPA GVNRNRKTNG SIPETATSGG CQPPGDSATG
     FHREGPTSSA TLKDLESPCQ ERAVVLDSTS VKISRLKNTI KSLKQQKKQV EHQLEEEKKA
     NNERQKAERE LEVQIQTLII QKEELNTDLY HMERSLRYFE EESKDLAVRL QHSLQCKGEL
     ESALSAVIAT EKKKANQLSS CSKAHTEWEL EQSLQDQALL KAQLTQLKES FQQLQLERDE
     CAEHIEGERA RWHQRMSKMS QEICTLKKEK QQDMRRVEEL ERSLSKLKNQ MAEPLPPEPP
     AVPSEVELQH LRKELERVAG ELQSQVKNNQ HISLLNRRQE ERIREQEERL RKQEERLQEQ
     HEKLRQLAKP QSVFEELNNE NKSTLQLEQQ VKELQEKLGE EHLEAASQQN QQLTAQLSLM
     ALPGEGHGGE HLDSEGEEAP QPMPSVPEDL ESREAMSSFM DHLKEKADLS ELVKKQELRF
     IQYWQERCHQ KIHHLLSEPG GRAKDAALGG GHHQAGAQGG DEGEAAGAAA DGIAAYSNYN
     NGHRKFLAAA HNSADEPGPG APAPQELGAA DKHGDLREVT LTSSAQGEAR EDPLLDKPTA
     QPIVQDHQEH PGLGSNCCVP LFCWAWLPRR RR