ID   GOG8Q_HUMAN             Reviewed;         632 AA.
AC   H3BV12;
DT   18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Golgin subfamily A member 8Q {ECO:0000305};
GN   Name=GOLGA8Q {ECO:0000312|HGNC:HGNC:44408};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000305}.
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DR   EMBL; AC026150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS86441.1; -.
DR   AlphaFoldDB; H3BV12; -.
DR   SMR; H3BV12; -.
DR   BioMuta; GOLGA8Q; -.
DR   jPOST; H3BV12; -.
DR   MassIVE; H3BV12; -.
DR   MaxQB; H3BV12; -.
DR   PaxDb; H3BV12; -.
DR   PeptideAtlas; H3BV12; -.
DR   PRIDE; H3BV12; -.
DR   Ensembl; ENST00000562783.2; ENSP00000457904.1; ENSG00000178115.12.
DR   MANE-Select; ENST00000562783.2; ENSP00000457904.1; NM_001355476.2; NP_001342405.1.
DR   UCSC; uc059hbl.1; human.
DR   GeneCards; GOLGA8Q; -.
DR   HGNC; HGNC:44408; GOLGA8Q.
DR   HPA; ENSG00000178115; Tissue enhanced (thyroid).
DR   neXtProt; NX_H3BV12; -.
DR   VEuPathDB; HostDB:ENSG00000178115; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00530000062932; -.
DR   HOGENOM; CLU_012403_1_2_1; -.
DR   InParanoid; H3BV12; -.
DR   PhylomeDB; H3BV12; -.
DR   TreeFam; TF316990; -.
DR   SignaLink; H3BV12; -.
DR   Pharos; H3BV12; Tdark.
DR   PRO; PR:H3BV12; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   Bgee; ENSG00000178115; Expressed in right lobe of thyroid gland and 97 other tissues.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043937; GM130_C.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 1.
DR   Pfam; PF19046; GM130_C; 1.
DR   Pfam; PF15070; GOLGA2L5; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..632
FT                   /note="Golgin subfamily A member 8Q"
FT                   /id="PRO_0000444803"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          504..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          552..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          86..148
FT                   /evidence="ECO:0000255"
FT   COILED          270..411
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   632 AA;  71646 MW;  CDC87B05BF000BE7 CRC64;
     MAEETQHNKL AAAKKKLKEY WQKNRPRVPA GVNRNRKTNG SIPETATSGG CQPPGDSATG
     FHREGPTSSA TLKDLESPCQ ERAVVLDSTS VKISRLKNTI KSLKQQKKQV EHQLEEEKKA
     NNERQKAERE LEVQIQTLII QKEELNTDLY HMERSLRYFE EESKDLAVRL QHSLQCKGEL
     ERALSAVIAT EKKKANQLSS CSKAHTEWEL EQSLQDQALL KAQLTQLKES FQQLQLERDE
     CAEHIEGERA RWHQRMSKML QEICTLKKEK QQDMRRVEEL ERSLSKLKNQ MAEPLPPEPP
     AVPSEVELQH LRKELERVAG ELQSQVKNNQ HISLLNRRQE ERIREQEERL RKQEERLQEQ
     HEKLRQLAKP QSVFEELNNE NKSTLQLEQQ VKELQEKLGE EHLEAASQQN QQLTAQLNLM
     ALPGEGHGGE HLDSEGEEAP QPMPSVPEDL ESREAMSSFM DHLKEKADLS ELVKKQELRF
     IQYWQERCHQ KIHHLLSEPG GRAKDAALGG GHHQAGAQGG DEGEAAGAAA DGIAAYSNYN
     NGHRKFLAAA HNSADEPGPG APAPQELGAA DKHGDLREVT LTSSAQGEAR EDPLLDKPTA
     QPIVQDHQEH PGLGSNCCVP LFCWAWLPRR RR