ID   GOG8S_HUMAN             Reviewed;         625 AA.
AC   H3BPF8;
DT   18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Golgin subfamily A member 8S {ECO:0000305};
GN   Name=GOLGA8S {ECO:0000312|HGNC:HGNC:44409};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000305}.
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DR   EMBL; AC100756; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3BPF8; -.
DR   SMR; H3BPF8; -.
DR   STRING; 9606.ENSP00000455298; -.
DR   BioMuta; GOLGA8S; -.
DR   jPOST; H3BPF8; -.
DR   MassIVE; H3BPF8; -.
DR   MaxQB; H3BPF8; -.
DR   PaxDb; H3BPF8; -.
DR   PeptideAtlas; H3BPF8; -.
DR   PRIDE; H3BPF8; -.
DR   Ensembl; ENST00000562295.1; ENSP00000455298.1; ENSG00000261739.2.
DR   MANE-Select; ENST00000562295.3; ENSP00000455298.2; NM_001395373.1; NP_001382302.1.
DR   UCSC; uc059gsm.1; human.
DR   GeneCards; GOLGA8S; -.
DR   HGNC; HGNC:44409; GOLGA8S.
DR   HPA; ENSG00000261739; Tissue enriched (testis).
DR   neXtProt; NX_H3BPF8; -.
DR   VEuPathDB; HostDB:ENSG00000261739; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00530000062932; -.
DR   HOGENOM; CLU_012403_1_2_1; -.
DR   InParanoid; H3BPF8; -.
DR   OMA; CQEPAVI; -.
DR   PhylomeDB; H3BPF8; -.
DR   TreeFam; TF316990; -.
DR   Pharos; H3BPF8; Tdark.
DR   PRO; PR:H3BPF8; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; H3BPF8; protein.
DR   Bgee; ENSG00000261739; Expressed in left testis and 90 other tissues.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043937; GM130_C.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 1.
DR   Pfam; PF19046; GM130_C; 1.
DR   Pfam; PF15070; GOLGA2L5; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..625
FT                   /note="Golgin subfamily A member 8S"
FT                   /id="PRO_0000444804"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          414..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..519
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          93..148
FT                   /evidence="ECO:0000255"
FT   COILED          210..262
FT                   /evidence="ECO:0000255"
FT   COILED          305..404
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   625 AA;  70417 MW;  6BF9E1BE9A470624 CRC64;
     MAEETRQSKL AAAKRKLKEY WQRNSPGVPA GAKRNRKTNG SIHETATSGG CHSPGDSATG
     IHGESPTSSA TLKDLESPCQ ELAVVPDSRS VKVSQLKNTI KSLKQQKKQV VHQLEEEKKA
     NNEKQKAERE LEVQIQRLNI QKGKLNTDLY HTKRSLRYFE EESKDLAVRL QHSLQRKGEL
     ERALSAVTAT QKKKAERFSS RSKARTEWKL EQSMREQALL KAQLTQLKES LKEVQLERDE
     YAEHLKGERA RWQQRMRKMS QEVCSLKKEK KHDKYRVETL ERSLSKLKNQ MAEPLPPEPP
     AVPSEAELQH LRKELERVAG ALQAQVEYNQ RISLLNEGQK ERLREQQERL PEQEERLQQL
     AEPQNSFKEL NNENKSVLQL EQQVKELQEK LGKERLEAAS QQKQQLTAQL SLMALPGEGD
     GGGHLDSEGE EAPRPIPSIP QDLESREAMS SFMDHLEEKA DLSELVKKQE LRFIQYWQER
     CHQKIHHLLS EPGGRAKDAA LGGGHHQAGA QGGDEDEAAG AAADGIAAYS NYNNGHRKFL
     AAAHNPADEP GPGAPAPQEL GAADKHGDLC EVSLTSSAQG EAREDPLLDK PTAQPIVQDH
     QEHPGLGNNC CVPFFCWAWL PRRRR