ID   GOG8T_HUMAN             Reviewed;         631 AA.
AC   H3BQL2;
DT   18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Golgin subfamily A member 8T {ECO:0000305};
GN   Name=GOLGA8T {ECO:0000312|HGNC:HGNC:44410};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA8 family. {ECO:0000305}.
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DR   EMBL; AC120045; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS86440.1; -.
DR   AlphaFoldDB; H3BQL2; -.
DR   SMR; H3BQL2; -.
DR   STRING; 9606.ENSP00000455826; -.
DR   BioMuta; GOLGA8T; -.
DR   jPOST; H3BQL2; -.
DR   MassIVE; H3BQL2; -.
DR   PaxDb; H3BQL2; -.
DR   PeptideAtlas; H3BQL2; -.
DR   PRIDE; H3BQL2; -.
DR   Ensembl; ENST00000569052.2; ENSP00000455826.1; ENSG00000261247.2.
DR   Ensembl; ENST00000640022.1; ENSP00000492105.1; ENSG00000284076.3.
DR   Ensembl; ENST00000646079.1; ENSP00000496287.1; ENSG00000284076.3.
DR   MANE-Select; ENST00000569052.2; ENSP00000455826.1; NM_001355469.2; NP_001342398.1.
DR   UCSC; uc059hav.1; human.
DR   GeneCards; GOLGA8T; -.
DR   HGNC; HGNC:44410; GOLGA8T.
DR   HPA; ENSG00000261247; Tissue enriched (testis).
DR   neXtProt; NX_H3BQL2; -.
DR   VEuPathDB; HostDB:ENSG00000261247; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00530000062932; -.
DR   HOGENOM; CLU_012403_1_2_1; -.
DR   InParanoid; H3BQL2; -.
DR   PhylomeDB; H3BQL2; -.
DR   TreeFam; TF316990; -.
DR   Pharos; H3BQL2; Tdark.
DR   PRO; PR:H3BQL2; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; H3BQL2; protein.
DR   Bgee; ENSG00000261247; Expressed in right testis and 90 other tissues.
DR   GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR   GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR043937; GM130_C.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   InterPro; IPR024858; Golgin_A.
DR   PANTHER; PTHR10881; PTHR10881; 1.
DR   Pfam; PF19046; GM130_C; 1.
DR   Pfam; PF15070; GOLGA2L5; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..631
FT                   /note="Golgin subfamily A member 8T"
FT                   /id="PRO_0000444805"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          86..148
FT                   /evidence="ECO:0000255"
FT   COILED          224..411
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..379
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   631 AA;  71644 MW;  1B0517D35923E076 CRC64;
     MAEETQHNKL AAAKKKLKEY WQKNSPRVPA GANRNRKTNG SIPEKATSGG CQPPRDSATG
     FHREGPTSSA TLKDLESPCQ ERAVVLDSRS VEISQLKNTI KSLKQQKKQV EHQLEEEKKA
     NNKKQKAKRV LEVQIQTLNI QKEELNTDLY HMKRSLRYFE EKSKDLAVRL QHSLQRKGEL
     ESVLSNVMAT QKKKANQLSS RSKARTEWKL EQSMREETLL KVQLTQLKES FQQVQLERDE
     YSEHLKGERA RWQQRMRKMS QEICTLKKEK QQDMRRVEEL ERSLSKLKNQ MAEPLPPEPP
     AVPSEVELQH LRKELERVAG ELQAQVKKNQ RISLLNQRQE ERIQEQEERL RKQEERIQEQ
     HKSLQQLAKP QSVFEEPNNE NKNALQLEQQ VKELQEKLGE EHLEAASQQN QQLTAQLSLM
     ALPGEGHGGE HLDSEGEEAP QPMPSVPEDL ESREAMSSFM DHLKEKADLS ELVKKELCFI
     HHWRDRRHQK THHLLSEPGG CAKDAALGGG HHQAGAQGGD EGEAAGAAAD GIAAYSNYNN
     GHRKFLAAAH NPADEPGPGA PAPQELGAAD KHGDLREVSL TSSAQGEARE DPLLDKPTAQ
     PIVQDHQEHP GLGSNCCVPF LCWAWLPRRR R