GOGC3_ARATH
ID GOGC3_ARATH Reviewed; 712 AA.
AC Q84WU4; Q9M311;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Golgin candidate 3;
DE Short=AtGC3;
DE AltName: Full=GRIP-related ARF-binding domain-containing Arabidopsis protein 1;
GN Name=GC3; Synonyms=GDAP1; OrderedLocusNames=At3g61570; ORFNames=F2A19.170;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], INTERACTION WITH ARF1, AND SUBCELLULAR
RP LOCATION.
RX PubMed=17307898; DOI=10.1104/pp.106.094953;
RA Matheson L.A., Hanton S.L., Rossi M., Latijnhouwers M., Stefano G.,
RA Renna L., Brandizzi F.;
RT "Multiple roles of ADP-ribosylation factor 1 in plant cells include
RT spatially regulated recruitment of coatomer and elements of the Golgi
RT matrix.";
RL Plant Physiol. 143:1615-1627(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP SUBCELLULAR LOCATION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18182439; DOI=10.1093/jxb/erm304;
RA Latijnhouwers M., Gillespie T., Boevink P., Kriechbaumer V., Hawes C.,
RA Carvalho C.M.;
RT "Localization and domain characterization of Arabidopsis golgin
RT candidates.";
RL J. Exp. Bot. 58:4373-4386(2007).
CC -!- FUNCTION: Golgi matrix protein playing a role in tethering of vesicles
CC to Golgi membranes and in maintaining the overall structure of the
CC Golgi apparatus.
CC -!- SUBUNIT: Interacts with ARF1; preferentially with the active form of
CC the protein. {ECO:0000269|PubMed:17307898}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus. Endosome.
CC -!- DOMAIN: The C-terminal domain (551-712) is responsible for the Golgi
CC localization.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB71087.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; EU249332; ABY67252.1; -; mRNA.
DR EMBL; AL132962; CAB71087.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE80224.1; -; Genomic_DNA.
DR EMBL; BT002756; AAO22585.1; -; mRNA.
DR EMBL; AK226722; BAE98827.1; -; mRNA.
DR PIR; T47949; T47949.
DR RefSeq; NP_191716.2; NM_116022.5.
DR AlphaFoldDB; Q84WU4; -.
DR SMR; Q84WU4; -.
DR BioGRID; 10644; 1.
DR STRING; 3702.AT3G61570.1; -.
DR PaxDb; Q84WU4; -.
DR PRIDE; Q84WU4; -.
DR ProteomicsDB; 248439; -.
DR EnsemblPlants; AT3G61570.1; AT3G61570.1; AT3G61570.
DR GeneID; 825330; -.
DR Gramene; AT3G61570.1; AT3G61570.1; AT3G61570.
DR KEGG; ath:AT3G61570; -.
DR Araport; AT3G61570; -.
DR TAIR; locus:2082782; AT3G61570.
DR eggNOG; ENOG502QSWR; Eukaryota.
DR HOGENOM; CLU_023485_1_0_1; -.
DR InParanoid; Q84WU4; -.
DR OrthoDB; 1008112at2759; -.
DR PhylomeDB; Q84WU4; -.
DR PRO; PR:Q84WU4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q84WU4; baseline and differential.
DR Genevisible; Q84WU4; AT.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IDA:TAIR.
DR GO; GO:0031267; F:small GTPase binding; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0007030; P:Golgi organization; ISS:TAIR.
PE 1: Evidence at protein level;
KW Coiled coil; Endosome; Golgi apparatus; Reference proteome.
FT CHAIN 1..712
FT /note="Golgin candidate 3"
FT /id="PRO_0000348537"
FT DOMAIN 557..608
FT /note="GRIP"
FT REGION 23..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 65..134
FT /evidence="ECO:0000255"
FT COILED 197..313
FT /evidence="ECO:0000255"
FT COILED 340..558
FT /evidence="ECO:0000255"
FT COILED 659..690
FT /evidence="ECO:0000255"
FT COMPBIAS 34..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 81723 MW; 2F1A933D304B1736 CRC64;
MWSSIENMKA NLHKIVLDVH EDDEEEDDLH KYGSANGVSN SDRRNSSGFR SVSRYSISNG
IESPAHHEIE RYKAEIKKLQ ESESDIKALS VNYAALLREK EDQISRLNQE NGSLKQNLTS
TSAALKEART DISRGSNNYA IKGNNDQSPN RLHKSVSHLK SPNHMSNGKG KDTDSFIKEK
DLADMLEDRT KSMAAVQATE LAKEREKLRD FQLSLQEERK RSESFKEELE SMRLDKNKTS
MEISKMRSEL DAKLLEIKHL QMKLTGQESH AIGPGMEHLK EVNKALEKEN NELKLKRSEL
EAALEESRKL TNSKVFPDAT ESLTRHPSTL DKEKPESFPG KEEMEQSLQR LEMDLKETQR
ERDKARQELK RLKQHLLEKE TEESEKMDED SRLIEELRQT NEYQRSQISH LEKSLKQAIS
NQEDNRLSND NQIRKLKDTV DDLNQKLTNC LRTIESKNVE LLNLQTALGQ YYAEIEAKEH
FERELAMAKD ELMKLSARLK DSDERLESSN KEKEDVTSKL LHAEKVAAEW KNRVTKVEED
NAKVRRVLEQ SMTRLNRMSM ESDYLVDRRI VIKLLVTYFQ KNHNKEVLDL MVRMLGFSEE
DKERIGAAKQ GGGKGVVRGV LGFPGRFVGG ILGGKSAELH ANAASDNQSF ADLWVDFLLK
DAEERERREA EEAAASKAKQ DSERTRQEAA LHDSEFSTVP LRSSESNQRL SR
