GOGC4_ARATH
ID GOGC4_ARATH Reviewed; 725 AA.
AC Q8VYU6; O82351;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Golgin candidate 4;
DE Short=AtGC4;
GN Name=GC4; OrderedLocusNames=At2g46180; ORFNames=T3F17.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=18182439; DOI=10.1093/jxb/erm304;
RA Latijnhouwers M., Gillespie T., Boevink P., Kriechbaumer V., Hawes C.,
RA Carvalho C.M.;
RT "Localization and domain characterization of Arabidopsis golgin
RT candidates.";
RL J. Exp. Bot. 58:4373-4386(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Golgi matrix protein playing a role in tethering of vesicles
CC to Golgi membranes and in maintaining the overall structure of the
CC Golgi apparatus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:18182439}.
CC Note=Probably located to cisternal rims of cis or medial Golgi.
CC -!- DOMAIN: The C-terminal domain (556-725) is necessary and sufficient for
CC Golgi targeting.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC62888.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; EU249331; ABY67251.1; -; mRNA.
DR EMBL; AC005397; AAC62888.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC10653.1; -; Genomic_DNA.
DR EMBL; AY069912; AAL47462.1; -; mRNA.
DR EMBL; BT001025; AAN46779.1; -; mRNA.
DR PIR; F84899; F84899.
DR RefSeq; NP_850447.1; NM_180116.2.
DR AlphaFoldDB; Q8VYU6; -.
DR SMR; Q8VYU6; -.
DR STRING; 3702.AT2G46180.1; -.
DR iPTMnet; Q8VYU6; -.
DR PaxDb; Q8VYU6; -.
DR PRIDE; Q8VYU6; -.
DR ProteomicsDB; 248440; -.
DR EnsemblPlants; AT2G46180.1; AT2G46180.1; AT2G46180.
DR GeneID; 819225; -.
DR Gramene; AT2G46180.1; AT2G46180.1; AT2G46180.
DR KEGG; ath:AT2G46180; -.
DR Araport; AT2G46180; -.
DR TAIR; locus:2062984; AT2G46180.
DR eggNOG; ENOG502QSWR; Eukaryota.
DR HOGENOM; CLU_023485_1_0_1; -.
DR InParanoid; Q8VYU6; -.
DR OMA; FPGKEDM; -.
DR OrthoDB; 1008112at2759; -.
DR PhylomeDB; Q8VYU6; -.
DR PRO; PR:Q8VYU6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8VYU6; baseline and differential.
DR Genevisible; Q8VYU6; AT.
DR GO; GO:0005794; C:Golgi apparatus; IDA:TAIR.
DR GO; GO:0031267; F:small GTPase binding; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0007030; P:Golgi organization; ISS:TAIR.
PE 2: Evidence at transcript level;
KW Coiled coil; Golgi apparatus; Reference proteome.
FT CHAIN 1..725
FT /note="Golgin candidate 4"
FT /id="PRO_0000348538"
FT DOMAIN 562..613
FT /note="GRIP"
FT REGION 17..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 66..132
FT /evidence="ECO:0000255"
FT COILED 191..316
FT /evidence="ECO:0000255"
FT COILED 344..407
FT /evidence="ECO:0000255"
FT COILED 437..563
FT /evidence="ECO:0000255"
FT COMPBIAS 33..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..725
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 725 AA; 82866 MW; FC3C5B2E4049A00F CRC64;
MWSSVANLKE NLNKIAHDVH DDDEDDDEDL TIYGSTNGGT DRRNSNGFRY SRSPMANGFE
SPVNPEIERY KAEINKLQKS ESEIKALSVN YAALLKEKED QISRLNQENG SLKQNLTSTN
AALKESRLDL SRASNNNAIK GNGDHSPNRS QRSPTNWKNR NQMNNGIASK PNGTENDSES
HKKEKEFAEM LEERTRSMAS AQARELEKER EKSANLQILL QEERKQNETF KEELQSLRLD
KEKTLMESNK VRRELDAKLA EIRQLQMKLN GGEQHAFGIS RENLKEVNKA LEKENNELKL
KRSELEAALE ASQKSTSRKL FPKSTEDLSR HLSSLDEEKA GTFPGKEDME KSLQRLEKEL
EEARREKDKA RQELKRLKQH LLEKETEESE KMDEDSRLID ELRQTNEYQR SQILGLEKAL
RQTMANQEEI KSSSDLEIRK SKGIIEDLNQ KLANCLRTID SKNVELLNLQ TALGQYYAEI
EAKEHFEREL AVAKEDAMKL SARLKDVDEQ LESSKKEKEE ITSKVLHAEN IAAEWKNRVS
KVEDDNAKVR RVLEQSMTRL NRMSMDSDFL VDRRIVIKLL VTYFQRNHSR EVLDLMVRML
GFSEEEKQRI GLAQQGAAGK GVVRGVLGFP GRLVGGILGG GGGSPDSHPN MASDNQSFAD
MWVEFLLKDA EERERREAED AANKEQEKAT VSSTQRPKYE QSDSEFSTVP LTSSNSNHRL
SRLLT
