GOGC5_ARATH
ID GOGC5_ARATH Reviewed; 956 AA.
AC Q0WVL7; Q56X06; Q9CA88;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Golgin candidate 5;
DE Short=AtGC5;
GN Name=GC5; OrderedLocusNames=At1g79830; ORFNames=F19K16.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, INTERACTION WITH RABH1B;
RP RABH1C; RABD1 AND RABD2A, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18182439; DOI=10.1093/jxb/erm304;
RA Latijnhouwers M., Gillespie T., Boevink P., Kriechbaumer V., Hawes C.,
RA Carvalho C.M.;
RT "Localization and domain characterization of Arabidopsis golgin
RT candidates.";
RL J. Exp. Bot. 58:4373-4386(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-793, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-793, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: Golgi matrix protein playing a role in tethering of vesicles
CC to Golgi membranes and in maintaining the overall structure of the
CC Golgi apparatus. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with RABH1B and RABH1C, but not with RABD1 or
CC RABD2A. {ECO:0000269|PubMed:18182439}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:18182439}.
CC Cytoplasm {ECO:0000269|PubMed:18182439}. Note=May be located to the
CC trans-Golgi or trans-Golgi network (TGN).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q0WVL7-1; Sequence=Displayed;
CC -!- DOMAIN: The C-terminal domain (817-956) is necessary and sufficient for
CC Golgi and cytoplasm targeting.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG52248.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD94181.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; EU249329; ABY67249.1; -; mRNA.
DR EMBL; AC011717; AAG52248.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE36307.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36308.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36310.1; -; Genomic_DNA.
DR EMBL; AK221873; BAD94181.1; ALT_INIT; mRNA.
DR EMBL; AK226727; BAE98831.1; -; mRNA.
DR PIR; C96829; C96829.
DR RefSeq; NP_001117622.1; NM_001124150.1. [Q0WVL7-1]
DR RefSeq; NP_001185442.1; NM_001198513.2. [Q0WVL7-1]
DR RefSeq; NP_178101.3; NM_106632.4. [Q0WVL7-1]
DR AlphaFoldDB; Q0WVL7; -.
DR SMR; Q0WVL7; -.
DR BioGRID; 29540; 4.
DR STRING; 3702.AT1G79830.4; -.
DR iPTMnet; Q0WVL7; -.
DR PaxDb; Q0WVL7; -.
DR PRIDE; Q0WVL7; -.
DR ProteomicsDB; 248452; -. [Q0WVL7-1]
DR EnsemblPlants; AT1G79830.1; AT1G79830.1; AT1G79830. [Q0WVL7-1]
DR EnsemblPlants; AT1G79830.2; AT1G79830.2; AT1G79830. [Q0WVL7-1]
DR EnsemblPlants; AT1G79830.3; AT1G79830.3; AT1G79830. [Q0WVL7-1]
DR GeneID; 844322; -.
DR Gramene; AT1G79830.1; AT1G79830.1; AT1G79830. [Q0WVL7-1]
DR Gramene; AT1G79830.2; AT1G79830.2; AT1G79830. [Q0WVL7-1]
DR Gramene; AT1G79830.3; AT1G79830.3; AT1G79830. [Q0WVL7-1]
DR KEGG; ath:AT1G79830; -.
DR Araport; AT1G79830; -.
DR eggNOG; KOG4673; Eukaryota.
DR InParanoid; Q0WVL7; -.
DR PhylomeDB; Q0WVL7; -.
DR PRO; PR:Q0WVL7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q0WVL7; baseline and differential.
DR Genevisible; Q0WVL7; AT.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR InterPro; IPR022092; TMF_DNA-bd.
DR InterPro; IPR022091; TMF_TATA-bd.
DR Pfam; PF12329; TMF_DNA_bd; 1.
DR Pfam; PF12325; TMF_TATA_bd; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Cytoplasm; Golgi apparatus;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..956
FT /note="Golgin candidate 5"
FT /id="PRO_0000348539"
FT REGION 70..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 333..765
FT /evidence="ECO:0000255"
FT COILED 851..951
FT /evidence="ECO:0000255"
FT COMPBIAS 79..106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..152
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..216
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 793
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19245862,
FT ECO:0007744|PubMed:19376835"
FT CONFLICT 670
FT /note="N -> D (in Ref. 4; BAD94181)"
FT /evidence="ECO:0000305"
FT CONFLICT 786
FT /note="L -> F (in Ref. 4; BAD94181)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 956 AA; 108354 MW; 15DF42E0DD4562DD CRC64;
MAWFSGKVSL GGFPDLTGAV NKFQESVKNI EKNFDNALGF DDKSDSAAED AASSMWPPAV
DTKSLFDPVM SFMGNTSDEK PDTLEDSVRT ENPSQIEQKE EEAGSVKLAT EQAVSVEANK
ETNVRREADQ ADNPEVTETV VLDPKDDEPQ SQILLEESSE YSLQTPESSG YKTSLQPNEK
LEMTASQDSQ PEQPKSEAEE SQPEDSEAKE VTVENKDTVH SPVLDGQHKI TYMDETTNEQ
EILGENLEGR TSSKNFEVSP DINHVNRIES PVAHPSLIFE SDGSPYESSI PKRSSSDEIS
ERIVDFVSRE IDSRLDTSEL NESQRSSSAT NVSDSADVIL ELEKTKKEIK MLENALQGAA
RQAQAKADEI AKLMHENEQL KSVTEDLKRK SNEAEVESLR EEYHQRVATL ERKVYALTKE
RDTLRREQNK KSDAAALLKE KDEIINQVMA EGEELSKKQA AQEAQIRKLR AQIREAEEEK
KGLITKLQSE ENKVESIKRD KTATEKLLQE TIEKHQAELT SQKDYYSNAL AAAKEAQALA
EERTNNEARS ELENRLKEAG ERESMLVQAL EELRQTLSKK EQQAVYREDM FRGEIEDLQR
RYQASERRCE ELITQVPEST RPLLRQIEAM QETSYRTAEA WAAVERTLNS RLQEAESKAA
TAEERERSVN ERLSQTLSRI NVLEAQLSCL RAEQGQLSKS LEKERQRAAE NRQEYLAAKE
EADTLEGRAN QLEVEIRELR RKHKQELQEV LLHNELIQKD LEREKASRLD LERTARINSS
AVSEQLPIAR QNSAFENGSL PRKLSSASSL GSMEESYFLQ ASLDSSDKFS EKRSMPEATM
SPYYMKSITP SAYEATLRQK EGELASYMTR LASMESIRDS LAEELVKMTA ECEKLRGEAD
RVPGIKAELE ALRQRHAAAL ELMGERDEEL EELRADIVDL KEMYREQVNM LVNKIQ
