ID   GON2_ALLMI              Reviewed;          10 AA.
AC   P68073; P20408; P37043; P81750;
DT   25-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   29-SEP-2021, entry version 35.
DE   RecName: Full=Gonadoliberin-2;
DE   AltName: Full=Gonadoliberin II;
DE   AltName: Full=Gonadotropin-releasing hormone II;
DE            Short=GnRH-II;
DE   AltName: Full=Luliberin II;
DE   AltName: Full=Luteinizing hormone-releasing hormone II;
DE            Short=LH-RH II;
GN   Name=GNRH2;
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT
RP   GLY-10.
RC   TISSUE=Brain;
RX   PubMed=1882082; DOI=10.1016/0167-0115(91)90206-v;
RA   Lovejoy D.A., Fischer W.H., Parker D.B., McRory J.E., Park M., Lance V.,
RA   Swanson P., Rivier J.E., Sherwood N.M.;
RT   "Primary structure of two forms of gonadotropin-releasing hormone from
RT   brains of the American alligator (Alligator mississippiensis).";
RL   Regul. Pept. 33:105-116(1991).
CC   -!- FUNCTION: Stimulates the secretion of gonadotropins.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the GnRH family. {ECO:0000305}.
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DR   PIR; B60066; RHAQ2.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002012; GnRH.
DR   Pfam; PF00446; GnRH; 1.
DR   PROSITE; PS00473; GNRH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Pyrrolidone carboxylic acid;
KW   Secreted.
FT   PEPTIDE         1..10
FT                   /note="Gonadoliberin-2"
FT                   /id="PRO_0000043950"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:1882082"
FT   MOD_RES         10
FT                   /note="Glycine amide"
FT                   /evidence="ECO:0000269|PubMed:1882082"
SQ   SEQUENCE   10 AA;  1254 MW;  284B2E437871F5A3 CRC64;
     QHWSHGWYPG