ID   GON7_BOVIN              Reviewed;         100 AA.
AC   P0C8B3;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=EKC/KEOPS complex subunit GON7 {ECO:0000305};
GN   Name=GON7 {ECO:0000250|UniProtKB:Q9BXV9};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the EKC/KEOPS complex that is required for the
CC       formation of a threonylcarbamoyl group on adenosine at position 37
CC       (t(6)A37) in tRNAs that read codons beginning with adenine. The complex
CC       is probably involved in the transfer of the threonylcarbamoyl moiety of
CC       threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 plays a
CC       supporting role to the catalytic subunit OSGEP in the complex.
CC       {ECO:0000250|UniProtKB:Q9BXV9}.
CC   -!- SUBUNIT: Component of the EKC/KEOPS complex composed of at least GON7,
CC       TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
CC       {ECO:0000250|UniProtKB:Q9BXV9}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BXV9}.
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DR   EMBL; BC112473; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001160031.1; NM_001166559.1.
DR   AlphaFoldDB; P0C8B3; -.
DR   SMR; P0C8B3; -.
DR   STRING; 9913.ENSBTAP00000056584; -.
DR   PaxDb; P0C8B3; -.
DR   Ensembl; ENSBTAT00000063539; ENSBTAP00000056584; ENSBTAG00000046990.
DR   GeneID; 505131; -.
DR   KEGG; bta:505131; -.
DR   CTD; 84520; -.
DR   VEuPathDB; HostDB:ENSBTAG00000046990; -.
DR   VGNC; VGNC:29496; GON7.
DR   eggNOG; ENOG502SW4V; Eukaryota.
DR   GeneTree; ENSGT00490000044274; -.
DR   HOGENOM; CLU_180906_0_0_1; -.
DR   InParanoid; P0C8B3; -.
DR   OMA; PCEAPGD; -.
DR   OrthoDB; 1575198at2759; -.
DR   Proteomes; UP000009136; Chromosome 21.
DR   Bgee; ENSBTAG00000046990; Expressed in caput epididymis and 104 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0000408; C:EKC/KEOPS complex; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0002949; P:tRNA threonylcarbamoyladenosine modification; ISS:UniProtKB.
DR   InterPro; IPR027893; GON7_meta.
DR   PANTHER; PTHR37363; PTHR37363; 1.
DR   Pfam; PF15387; DUF4611; 1.
PE   3: Inferred from homology;
KW   Acetylation; Nucleus; Reference proteome.
FT   CHAIN           1..100
FT                   /note="EKC/KEOPS complex subunit GON7"
FT                   /id="PRO_0000352800"
FT   REGION          50..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..100
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BXV9"
SQ   SEQUENCE   100 AA;  10966 MW;  3DF060543E1BCA32 CRC64;
     MELLGEYIGL EGRRQQLRVP CEAPGVTDPF QSLLSGVAQM RELVTELFGS QVQQEAQDRV
     TAAPDEALDG DDEDDSEDEN NTDNRTNSDG PSAKRQKTPS