ID   GON7_DEBHA              Reviewed;         110 AA.
AC   Q6BVJ8;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=EKC/KEOPS complex subunit GON7;
GN   Name=GON7; OrderedLocusNames=DEHA2C02090g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the EKC/KEOPS complex that is required for the
CC       formation of a threonylcarbamoyl group on adenosine at position 37
CC       (t(6)A37) in tRNAs that read codons beginning with adenine. The complex
CC       is probably involved in the transfer of the threonylcarbamoyl moiety of
CC       threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely
CC       plays a supporting role to the catalytic subunit KAE1 in the complex.
CC       The EKC/KEOPS complex also promotes both telomere uncapping and
CC       telomere elongation. The complex is required for efficient recruitment
CC       of transcriptional coactivators (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the EKC/KEOPS complex composed of at least BUD32,
CC       CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, telomere
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GON7 family. {ECO:0000305}.
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DR   EMBL; CR382135; CAG85807.1; -; Genomic_DNA.
DR   RefSeq; XP_457771.1; XM_457771.1.
DR   AlphaFoldDB; Q6BVJ8; -.
DR   SMR; Q6BVJ8; -.
DR   STRING; 4959.XP_457771.1; -.
DR   EnsemblFungi; CAG85807; CAG85807; DEHA2C02090g.
DR   GeneID; 2900748; -.
DR   KEGG; dha:DEHA2C02090g; -.
DR   VEuPathDB; FungiDB:DEHA2C02090g; -.
DR   eggNOG; ENOG502S429; Eukaryota.
DR   HOGENOM; CLU_151420_0_0_1; -.
DR   InParanoid; Q6BVJ8; -.
DR   OMA; QINVYLT; -.
DR   OrthoDB; 1575178at2759; -.
DR   Proteomes; UP000000599; Chromosome C.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR014849; EKC/KEOPS_Gon7.
DR   Pfam; PF08738; Gon7; 1.
PE   3: Inferred from homology;
KW   Activator; Chromosome; Nucleus; Reference proteome; Telomere;
KW   Transcription; Transcription regulation; tRNA processing.
FT   CHAIN           1..110
FT                   /note="EKC/KEOPS complex subunit GON7"
FT                   /id="PRO_0000278922"
FT   REGION          16..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..101
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   110 AA;  12293 MW;  03218B80836A243C CRC64;
     MLDPLVPTAV YKAPDFTEGQ KFHPGEGPHT TNGKTTQISD IVIKAGGEDR DKPSDAKDTQ
     LGQLRAKLTT LQDQLNIFLT KRMDHEKSRS QEEKDLERQV LDEGVDDDSD