GOSR1_CAEBR
ID GOSR1_CAEBR Reviewed; 234 AA.
AC A8XLW0;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Golgi SNAP receptor complex member 1 {ECO:0000250|UniProtKB:Q95ZW1};
DE AltName: Full=28 kDa Golgi SNARE protein {ECO:0000250|UniProtKB:Q95ZW1};
DE Short=GOS-28 {ECO:0000250|UniProtKB:Q95ZW1};
GN Name=gos-28 {ECO:0000312|WormBase:CBG15298};
GN Synonyms=gosr-1 {ECO:0000250|UniProtKB:Q95ZW1},
GN gs28 {ECO:0000250|UniProtKB:Q95ZW1}; ORFNames=CBG15298;
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238;
RN [1] {ECO:0000312|EMBL:CAP33635.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16 {ECO:0000312|EMBL:CAP33635.1};
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R.M., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: Involved in transport from the ER to the Golgi apparatus as
CC well as in intra-Golgi transport. It belongs to a super-family of
CC proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive
CC factor) attachment protein receptor. Cooperates with ykt-6 for proper
CC expression of Golgi-resident proteins. Required along with ykt-6 for
CC normal embryonic development, seam cell division or differentiation,
CC and ray formation (By similarity). {ECO:0000250|UniProtKB:Q95ZW1}.
CC -!- SUBUNIT: Component of several multiprotein Golgi SNARE complexes.
CC {ECO:0000250|UniProtKB:O95249}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:O95249}; Single-pass type IV membrane protein
CC {ECO:0000250|UniProtKB:O95249}.
CC -!- SIMILARITY: Belongs to the GOSR1 family. {ECO:0000255}.
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DR EMBL; HE601407; CAP33635.1; -; Genomic_DNA.
DR RefSeq; XP_002643125.1; XM_002643079.1.
DR AlphaFoldDB; A8XLW0; -.
DR SMR; A8XLW0; -.
DR STRING; 6238.CBG15298; -.
DR EnsemblMetazoa; CBG15298.1; CBG15298.1; WBGene00035605.
DR GeneID; 8585119; -.
DR KEGG; cbr:CBG_15298; -.
DR CTD; 8585119; -.
DR WormBase; CBG15298; CBP03713; WBGene00035605; Cbr-gos-28.
DR eggNOG; KOG3208; Eukaryota.
DR HOGENOM; CLU_078034_0_1_1; -.
DR InParanoid; A8XLW0; -.
DR OMA; RDYGSEY; -.
DR OrthoDB; 1319902at2759; -.
DR Proteomes; UP000008549; Chromosome III.
DR GO; GO:0005801; C:cis-Golgi network; IBA:GO_Central.
DR GO; GO:0005797; C:Golgi medial cisterna; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR InterPro; IPR023601; Golgi_SNAP_su1.
DR PANTHER; PTHR21094; PTHR21094; 1.
DR PIRSF; PIRSF027109; Golgi_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil; ER-Golgi transport; Golgi apparatus; Membrane;
KW Protein transport; Receptor; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..234
FT /note="Golgi SNAP receptor complex member 1"
FT /id="PRO_0000415756"
FT TOPO_DOM 1..212
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q95ZW1, ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000250|UniProtKB:Q95ZW1, ECO:0000255"
FT TOPO_DOM 234
FT /note="Vesicular"
FT /evidence="ECO:0000250|UniProtKB:Q95ZW1, ECO:0000255"
FT COILED 54..121
FT /evidence="ECO:0000250|UniProtKB:Q95ZW1, ECO:0000255"
SQ SEQUENCE 234 AA; 26717 MW; 1EE1674CABAEB227 CRC64;
MSETWEALRK KARSTENSID VKLVSLNKLT ASSHGGFDID EKTVSSRQTT FRTVTTEIEG
LIEQLTNIND DMNDVAGAQS SASWASNPAI QHTLRRHREI LRDYGSEYRR ARDNVDQVLQ
RELLLSSSNN ESRNPAVNNR ARGYDMYLKE NDHINACDRL LDEQIEMAMS TKENVARQGI
NLRGISNRLH YITKKYPAIN NLMQKIKTKK QKNTMILAGV ISACLIFTIF WIIN
