ID   GOSR2_CAEBR             Reviewed;         212 AA.
AC   A8XP14;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Golgi SNAP receptor complex member 2 homolog memb-1 {ECO:0000250|UniProtKB:P41941};
GN   Name=memb-1 {ECO:0000312|WormBase:CBG16136};
GN   Synonyms=gosr-2.1 {ECO:0000312|WormBase:CBG16136};
GN   ORFNames=CBG16136 {ECO:0000312|WormBase:CBG16136};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Involved in transport of proteins from the cis/medial-Golgi
CC       to the trans-Golgi network. {ECO:0000250|UniProtKB:O35165}.
CC   -!- SUBUNIT: Part of a unique SNARE complex.
CC       {ECO:0000250|UniProtKB:O35165}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250|UniProtKB:O35165}; Single-pass type IV membrane protein
CC       {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:O35165}.
CC       Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35165}.
CC       Note=Concentrated most in the intermediate compartment/cis-Golgi
CC       network and the cis-Golgi cisternae 1 and 2. Greatly reduced in
CC       concentration at the trans end of the Golgi apparatus.
CC       {ECO:0000250|UniProtKB:O35165}.
CC   -!- SIMILARITY: Belongs to the GOSR2 family. {ECO:0000255}.
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DR   EMBL; HE600961; CAP34254.3; -; Genomic_DNA.
DR   RefSeq; XP_002643475.1; XM_002643429.1.
DR   AlphaFoldDB; A8XP14; -.
DR   SMR; A8XP14; -.
DR   STRING; 6238.CBG16136; -.
DR   GeneID; 8585468; -.
DR   KEGG; cbr:CBG_16136; -.
DR   CTD; 8585468; -.
DR   WormBase; CBG16136; CBP30258; WBGene00036173; Cbr-memb-1.
DR   eggNOG; KOG3251; Eukaryota.
DR   HOGENOM; CLU_083740_0_0_1; -.
DR   InParanoid; A8XP14; -.
DR   OMA; RMRVDQL; -.
DR   OrthoDB; 1139640at2759; -.
DR   Proteomes; UP000008549; Chromosome X.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031902; C:late endosome membrane; IBA:GO_Central.
DR   GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR   InterPro; IPR027027; GOSR2/Membrin/Bos1.
DR   PIRSF; PIRSF028865; Membrin-2; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Golgi apparatus; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..212
FT                   /note="Golgi SNAP receptor complex member 2 homolog memb-1"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000351209"
FT   TOPO_DOM        1..189
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        211..212
FT                   /note="Vesicular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   212 AA;  24568 MW;  AF059F28D140CAE9 CRC64;
     MEAQYQSTNF LLQKVQHDLG RLEGTQNEQD AQVVVQSIYG DISTLKDNLQ ALDNYVSREQ
     PARRQAARMR VDQLRMDVQR VDMAVSAVHT RMTQRWRSAS EREELLSARY RPNDTALSIG
     DHELQLNDRL HSSHNRLDEL ISQGSAVLDN LKSQHFSLRG VSRKMHDIGQ ALGLSNSTLQ
     VIDRRVREDW IFVIGCIVCC IFMYAFYRFW RG