GOT1A_BOVIN
ID GOT1A_BOVIN Reviewed; 132 AA.
AC Q2NKV8;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Vesicle transport protein GOT1A;
DE AltName: Full=Golgi transport 1 homolog A;
GN Name=GOLT1A {ECO:0000250|UniProtKB:Q6ZVE7};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1] {ECO:0000312|EMBL:AAI11611.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford {ECO:0000312|EMBL:AAI11611.1};
RC TISSUE=Testis {ECO:0000312|EMBL:AAI11611.1};
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in fusion of ER-derived transport vesicles
CC with the Golgi complex. {ECO:0000250|UniProtKB:Q9Y3E0}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GOT1 family. {ECO:0000255}.
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DR EMBL; BC111610; AAI11611.1; -; mRNA.
DR RefSeq; NP_001068829.1; NM_001075361.2.
DR AlphaFoldDB; Q2NKV8; -.
DR STRING; 9913.ENSBTAP00000013429; -.
DR PaxDb; Q2NKV8; -.
DR Ensembl; ENSBTAT00000013429; ENSBTAP00000013429; ENSBTAG00000010177.
DR GeneID; 508464; -.
DR KEGG; bta:508464; -.
DR CTD; 127845; -.
DR VEuPathDB; HostDB:ENSBTAG00000010177; -.
DR VGNC; VGNC:29494; GOLT1A.
DR eggNOG; KOG1743; Eukaryota.
DR GeneTree; ENSGT00390000014507; -.
DR HOGENOM; CLU_124519_2_0_1; -.
DR InParanoid; Q2NKV8; -.
DR OMA; KTFWFFF; -.
DR OrthoDB; 1534843at2759; -.
DR TreeFam; TF300267; -.
DR Proteomes; UP000009136; Chromosome 16.
DR Bgee; ENSBTAG00000010177; Expressed in ascending colon and 74 other tissues.
DR ExpressionAtlas; Q2NKV8; baseline and differential.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR InterPro; IPR045176; Got1.
DR InterPro; IPR007305; Vesicle_transpt_Got1/SFT2.
DR PANTHER; PTHR21493; PTHR21493; 1.
DR Pfam; PF04178; Got1; 1.
PE 2: Evidence at transcript level;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..132
FT /note="Vesicle transport protein GOT1A"
FT /id="PRO_0000237606"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 17..37
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..39
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 40..60
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 61..68
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 90..100
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 122..132
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 132 AA; 14817 MW; 111BB63777A19B0F CRC64;
MISITEWQKI GVGTTGFGIF FILFGMLLYF DSVLLAFGNL LFLTGLSLII GLRRTFSFFF
QRHKFKGTSF FLGGVVIVLL RWPLLGMCLE TYGFFSLFRG FFPVAFGFLG SASNIPFLSA
LFQRLQGTSS MV
