GOT1B_BOVIN
ID GOT1B_BOVIN Reviewed; 138 AA.
AC Q2YDE3;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Vesicle transport protein GOT1B;
DE AltName: Full=Golgi transport 1 homolog B;
GN Name=GOLT1B {ECO:0000250|UniProtKB:Q9Y3E0};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1] {ECO:0000312|EMBL:AAI10262.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus {ECO:0000312|EMBL:AAI10262.1};
RC TISSUE=Liver {ECO:0000312|EMBL:AAI10262.1};
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in fusion of ER-derived transport vesicles
CC with the Golgi complex. {ECO:0000250|UniProtKB:Q9Y3E0}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GOT1 family. {ECO:0000255}.
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DR EMBL; BC110261; AAI10262.1; -; mRNA.
DR RefSeq; NP_001039680.1; NM_001046215.2.
DR AlphaFoldDB; Q2YDE3; -.
DR STRING; 9913.ENSBTAP00000000490; -.
DR PaxDb; Q2YDE3; -.
DR PRIDE; Q2YDE3; -.
DR Ensembl; ENSBTAT00000000490; ENSBTAP00000000490; ENSBTAG00000000379.
DR GeneID; 515866; -.
DR KEGG; bta:515866; -.
DR CTD; 51026; -.
DR VEuPathDB; HostDB:ENSBTAG00000000379; -.
DR VGNC; VGNC:29495; GOLT1B.
DR eggNOG; KOG1743; Eukaryota.
DR GeneTree; ENSGT00390000014507; -.
DR HOGENOM; CLU_124519_1_0_1; -.
DR InParanoid; Q2YDE3; -.
DR OMA; IFVRWPV; -.
DR OrthoDB; 1534843at2759; -.
DR TreeFam; TF300267; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000000379; Expressed in oocyte and 105 other tissues.
DR ExpressionAtlas; Q2YDE3; baseline.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR InterPro; IPR045176; Got1.
DR InterPro; IPR007305; Vesicle_transpt_Got1/SFT2.
DR PANTHER; PTHR21493; PTHR21493; 1.
DR Pfam; PF04178; Got1; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Golgi apparatus; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..138
FT /note="Vesicle transport protein GOT1B"
FT /id="PRO_0000237609"
FT TOPO_DOM 1..9
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 10..30
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 31..32
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..53
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 54..68
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 90
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..109
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 110..138
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y3E0"
SQ SEQUENCE 138 AA; 15426 MW; 2EB85823C34EFAFA CRC64;
MISLTDTQKI GMGLTGFGVF FLFFGMILFF DKALLAIGNV LFVAGLAFVI GLERTFRFFF
QKHKMKATGF FLGGVFVVLI GWPLIGMIFE IYGFFLLFRG FFPVVVGFIR RVPVLGSLLN
LPGIRSFVDK VGESNNMV
