GOT1_CAEEL
ID GOT1_CAEEL Reviewed; 141 AA.
AC Q20263;
DT 10-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2006, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Probable Golgi transport protein 1;
DE AltName: Full=Enlarged amphid sheath glia protein 1 {ECO:0000312|WormBase:F41C3.4};
GN Name=eas-1 {ECO:0000312|WormBase:F41C3.4};
GN ORFNames=F41C3.4 {ECO:0000312|WormBase:F41C3.4};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: May be involved in fusion of ER-derived transport vesicles
CC with the Golgi complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GOT1 family. {ECO:0000305}.
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DR EMBL; BX284602; CCD65860.1; -; Genomic_DNA.
DR PIR; T16317; T16317.
DR RefSeq; NP_494847.2; NM_062446.4.
DR AlphaFoldDB; Q20263; -.
DR BioGRID; 39173; 1.
DR STRING; 6239.F41C3.4; -.
DR EPD; Q20263; -.
DR PaxDb; Q20263; -.
DR PeptideAtlas; Q20263; -.
DR EnsemblMetazoa; F41C3.4.1; F41C3.4.1; WBGene00018270.
DR GeneID; 173819; -.
DR KEGG; cel:CELE_F41C3.4; -.
DR UCSC; F41C3.4; c. elegans.
DR CTD; 173819; -.
DR WormBase; F41C3.4; CE39501; WBGene00018270; eas-1.
DR eggNOG; KOG1743; Eukaryota.
DR HOGENOM; CLU_124519_1_0_1; -.
DR InParanoid; Q20263; -.
DR OMA; KTFWFFF; -.
DR OrthoDB; 1534843at2759; -.
DR PhylomeDB; Q20263; -.
DR PRO; PR:Q20263; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00018270; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR InterPro; IPR045176; Got1.
DR InterPro; IPR007305; Vesicle_transpt_Got1/SFT2.
DR PANTHER; PTHR21493; PTHR21493; 1.
DR Pfam; PF04178; Got1; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..141
FT /note="Probable Golgi transport protein 1"
FT /id="PRO_0000218584"
FT TOPO_DOM 1..11
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 12..32
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 33
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 34..54
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..70
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..93
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..141
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 141 AA; 15634 MW; 4A71D242FE3C972B CRC64;
MMNFEVSTTK QIGVGLTTFG FFFIFLGVLM FLDSALLAIG NLLFIVGITF IIGVQRTLVF
FFEFRKLKGS ILFFGGILVV LFGYPLFGMI AECWGFIVLF GGFLPGIVNL LRSIPGISTI
TYLPGIRQVL DRLAPESKYP V
