GOT1_DICDI
ID GOT1_DICDI Reviewed; 138 AA.
AC Q54CL4;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Protein transport protein got1 homolog;
DE AltName: Full=Golgi transport protein 1;
GN Name=golt1; ORFNames=DDB_G0292868;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: May be involved in fusion of ER-derived transport vesicles
CC with the Golgi complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GOT1 family. {ECO:0000305}.
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DR EMBL; AAFI02000197; EAL60983.1; -; Genomic_DNA.
DR RefSeq; XP_629402.1; XM_629400.1.
DR AlphaFoldDB; Q54CL4; -.
DR STRING; 44689.DDB0266392; -.
DR PaxDb; Q54CL4; -.
DR EnsemblProtists; EAL60983; EAL60983; DDB_G0292868.
DR GeneID; 8628921; -.
DR KEGG; ddi:DDB_G0292868; -.
DR dictyBase; DDB_G0292868; golt1.
DR eggNOG; KOG1743; Eukaryota.
DR HOGENOM; CLU_124519_1_0_1; -.
DR InParanoid; Q54CL4; -.
DR OMA; VLMFFDR; -.
DR PhylomeDB; Q54CL4; -.
DR PRO; PR:Q54CL4; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR InterPro; IPR045176; Got1.
DR InterPro; IPR007305; Vesicle_transpt_Got1/SFT2.
DR PANTHER; PTHR21493; PTHR21493; 1.
DR Pfam; PF04178; Got1; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..138
FT /note="Protein transport protein got1 homolog"
FT /id="PRO_0000327623"
FT TOPO_DOM 1..7
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 8..28
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..30
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 31..51
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 52..62
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 63..82
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 83..87
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 109..138
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 138 AA; 15343 MW; 05451704B1367C14 CRC64;
MFTDQQKIGA MLSAMGLFFG FLGVLLFLDR NLLALGNLLL VSGIVLILGL QKTTKFFAQK
KKIKGTILFF FGIVVLLVTR WTFVGMVIEI FGFVNLFGDA FPIVISILRK LPIIGNILNH
PLVNRLLQKA DSGNELPF
