GOT1_SCHPO
ID GOT1_SCHPO Reviewed; 129 AA.
AC Q9USJ2;
DT 10-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Protein transport protein got1;
DE AltName: Full=Golgi transport protein 1;
GN Name=got1; ORFNames=SPCC4B3.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Nonessential protein required for the fusion of ER-derived
CC transport vesicles with the Golgi complex. Can be replaced by sft2 (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GOT1 family. {ECO:0000305}.
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DR EMBL; CU329672; CAB60676.1; -; Genomic_DNA.
DR PIR; T50446; T50446.
DR RefSeq; NP_588088.1; NM_001023080.2.
DR AlphaFoldDB; Q9USJ2; -.
DR BioGRID; 275455; 16.
DR STRING; 4896.SPCC4B3.02c.1; -.
DR PaxDb; Q9USJ2; -.
DR EnsemblFungi; SPCC4B3.02c.1; SPCC4B3.02c.1:pep; SPCC4B3.02c.
DR GeneID; 2538876; -.
DR KEGG; spo:SPCC4B3.02c; -.
DR PomBase; SPCC4B3.02c; got1.
DR VEuPathDB; FungiDB:SPCC4B3.02c; -.
DR eggNOG; KOG1743; Eukaryota.
DR HOGENOM; CLU_124519_1_0_1; -.
DR InParanoid; Q9USJ2; -.
DR OMA; VLMFFDR; -.
DR PhylomeDB; Q9USJ2; -.
DR PRO; PR:Q9USJ2; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0000137; C:Golgi cis cisterna; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; ISS:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISS:PomBase.
DR GO; GO:0006895; P:Golgi to endosome transport; ISS:PomBase.
DR GO; GO:0006886; P:intracellular protein transport; ISS:PomBase.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR InterPro; IPR045176; Got1.
DR InterPro; IPR007305; Vesicle_transpt_Got1/SFT2.
DR PANTHER; PTHR21493; PTHR21493; 1.
DR Pfam; PF04178; Got1; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..129
FT /note="Protein transport protein got1"
FT /id="PRO_0000218585"
FT TOPO_DOM 1..8
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 9..29
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 30
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 31..51
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 52..67
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 89..90
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 112..129
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 129 AA; 14707 MW; FF6B081F7A68A418 CRC64;
MWLSDLQKIG VGTTALGFLF MIMGIFMFFD GPLLSLGNLL LVFGFFMIAG FSKSVSFFLR
KDRMLGSISF FSGLLLTLFH FPIIGFFVEC LGFFNLFKVF YPLIISFLRT VPYIGPYIDR
LTSYQQSPV
