ID   GO_HHV7J                Reviewed;         313 AA.
AC   P52525;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   23-FEB-2022, entry version 63.
DE   RecName: Full=Glycoprotein U47 homolog;
GN   Name=U47;
OS   Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=57278;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8709220; DOI=10.1128/jvi.70.9.5975-5989.1996;
RA   Nicholas J.;
RT   "Determination and analysis of the complete nucleotide sequence of human
RT   herpesvirus.";
RL   J. Virol. 70:5975-5989(1996).
RN   [2]
RP   SUBCELLULAR LOCATION, INTERACTION WITH GLYCOPROTEIN H, AND INDUCTION.
RX   PubMed=16476971; DOI=10.1099/vir.0.81374-0;
RA   Sadaoka T., Yamanishi K., Mori Y.;
RT   "Human herpesvirus 7 U47 gene products are glycoproteins expressed in
RT   virions and associate with glycoprotein H.";
RL   J. Gen. Virol. 87:501-508(2006).
CC   -!- SUBUNIT: Interacts with glycoprotein (gH).
CC       {ECO:0000269|PubMed:16476971}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:16476971}. Note=Both
CC       the 51 kDa and 49 kDa are present in the virion.
CC       {ECO:0000269|PubMed:16476971}.
CC   -!- INDUCTION: Expressed late in the viral replication cycle.
CC       {ECO:0000269|PubMed:16476971}.
CC   -!- PTM: A long 51 kDa and a short 49 kDa protein are produced possibly by
CC       proteolytic cleavage. {ECO:0000250|UniProtKB:P30005}.
CC   -!- PTM: N-glycosylated with high-mannose and complex glycans.
CC       {ECO:0000269|PubMed:16476971}.
CC   -!- SIMILARITY: Belongs to the herpesviridae U47 family. {ECO:0000305}.
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DR   EMBL; U43400; AAC54709.1; -; Genomic_DNA.
DR   PIR; T41949; T41949.
DR   RefSeq; YP_073787.1; NC_001716.2.
DR   SMR; P52525; -.
DR   DNASU; 3289505; -.
DR   GeneID; 3289505; -.
DR   KEGG; vg:3289505; -.
DR   Proteomes; UP000009246; Genome.
DR   InterPro; IPR008645; Roseolovirus_U47.
DR   Pfam; PF05467; Herpes_U47; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Late protein; Reference proteome; Virion.
FT   CHAIN           1..313
FT                   /note="Glycoprotein U47 homolog"
FT                   /id="PRO_0000116324"
FT   REGION          274..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        40
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        43
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        127
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        164
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        207
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        227
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        236
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        259
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        307
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        310
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   313 AA;  36694 MW;  1E7200AFD4FC347F CRC64;
     MKNKMYSMLV FTLISFLFYS YLIIWTPVLS VCSEKISFVN LTNFSMWPKF AKFHYESFEK
     TYIQSCDIPI SKNCFKQILF WSFRLSQKKN ICLSKINMLY LDNFPRWTLH FEFPTKTNRK
     RHVYLDNISF LYLVFATLAF KTMDDSCVNK IPFEVLASHL FKINFSQNKI ETIFQDLQNH
     TEAQLFSREN SEQLFSFTNF IYYFVYNRTD CKNSISKFFY NSVNTRNVST PFGVTNFSLV
     RGIMSPIQSF KGNLMFLENK TKVTKPTAIP NAVTSEPTKF FPSTRGTSSM QASQQTSSFP
     TTFFTTNHSN TST