GP152_HUMAN
ID GP152_HUMAN Reviewed; 470 AA.
AC Q8TDT2; Q0VD88; Q86SM0;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Probable G-protein coupled receptor 152;
DE AltName: Full=G-protein coupled receptor PGR5;
GN Name=GPR152; Synonyms=PGR5;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Retina;
RA Bonner T.I., Nagle J.W., Kauffman D.;
RT "Complete coding sequence of GPR152.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12044878; DOI=10.1016/s0014-5793(02)02775-8;
RA Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S.;
RT "Identification of G protein-coupled receptor genes from the human genome
RT sequence.";
RL FEBS Lett. 520:97-101(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,
RA Tsutsumi S., Aburatani H., Asai K., Akiyama Y.;
RT "Genome-wide discovery and analysis of human seven transmembrane helix
RT receptor genes.";
RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 94-197.
RX PubMed=12679517; DOI=10.1073/pnas.0230374100;
RA Vassilatis D.K., Hohmann J.G., Zeng H., Li F., Ranchalis J.E.,
RA Mortrud M.T., Brown A., Rodriguez S.S., Weller J.R., Wright A.C.,
RA Bergmann J.E., Gaitanaris G.A.;
RT "The G protein-coupled receptor repertoires of human and mouse.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003).
CC -!- FUNCTION: Orphan receptor.
CC -!- INTERACTION:
CC Q8TDT2; Q9H172: ABCG4; NbExp=3; IntAct=EBI-13345167, EBI-8584118;
CC Q8TDT2; O95870: ABHD16A; NbExp=3; IntAct=EBI-13345167, EBI-348517;
CC Q8TDT2; Q96CM8: ACSF2; NbExp=3; IntAct=EBI-13345167, EBI-2876502;
CC Q8TDT2; Q15848: ADIPOQ; NbExp=3; IntAct=EBI-13345167, EBI-10827839;
CC Q8TDT2; Q6RW13-2: AGTRAP; NbExp=3; IntAct=EBI-13345167, EBI-11522760;
CC Q8TDT2; Q9NVV5-2: AIG1; NbExp=3; IntAct=EBI-13345167, EBI-11957045;
CC Q8TDT2; Q86W74-2: ANKRD46; NbExp=3; IntAct=EBI-13345167, EBI-12109402;
CC Q8TDT2; O95236-2: APOL3; NbExp=3; IntAct=EBI-13345167, EBI-11976321;
CC Q8TDT2; Q96PS8: AQP10; NbExp=3; IntAct=EBI-13345167, EBI-12820279;
CC Q8TDT2; Q92482: AQP3; NbExp=3; IntAct=EBI-13345167, EBI-2808854;
CC Q8TDT2; Q13520: AQP6; NbExp=3; IntAct=EBI-13345167, EBI-13059134;
CC Q8TDT2; Q15041: ARL6IP1; NbExp=3; IntAct=EBI-13345167, EBI-714543;
CC Q8TDT2; Q9H2C2: ARV1; NbExp=3; IntAct=EBI-13345167, EBI-11724186;
CC Q8TDT2; P27449: ATP6V0C; NbExp=3; IntAct=EBI-13345167, EBI-721179;
CC Q8TDT2; Q8NFL0: B3GNT7; NbExp=3; IntAct=EBI-13345167, EBI-17211590;
CC Q8TDT2; P23560-2: BDNF; NbExp=3; IntAct=EBI-13345167, EBI-12275524;
CC Q8TDT2; O15155: BET1; NbExp=3; IntAct=EBI-13345167, EBI-749204;
CC Q8TDT2; O95393: BMP10; NbExp=3; IntAct=EBI-13345167, EBI-3922513;
CC Q8TDT2; Q12982: BNIP2; NbExp=3; IntAct=EBI-13345167, EBI-752094;
CC Q8TDT2; Q12983: BNIP3; NbExp=3; IntAct=EBI-13345167, EBI-749464;
CC Q8TDT2; Q86Z23: C1QL4; NbExp=3; IntAct=EBI-13345167, EBI-12062109;
CC Q8TDT2; P07357: C8A; NbExp=3; IntAct=EBI-13345167, EBI-9021639;
CC Q8TDT2; Q9P0B6: CCDC167; NbExp=3; IntAct=EBI-13345167, EBI-9083477;
CC Q8TDT2; P13236: CCL4; NbExp=3; IntAct=EBI-13345167, EBI-2873970;
CC Q8TDT2; Q8NHW4: CCL4L2; NbExp=3; IntAct=EBI-13345167, EBI-10271156;
CC Q8TDT2; P19397: CD53; NbExp=3; IntAct=EBI-13345167, EBI-6657396;
CC Q8TDT2; P21854: CD72; NbExp=3; IntAct=EBI-13345167, EBI-307924;
CC Q8TDT2; P60033: CD81; NbExp=3; IntAct=EBI-13345167, EBI-712921;
CC Q8TDT2; O14735: CDIPT; NbExp=3; IntAct=EBI-13345167, EBI-358858;
CC Q8TDT2; O95674: CDS2; NbExp=3; IntAct=EBI-13345167, EBI-3913685;
CC Q8TDT2; Q99675: CGRRF1; NbExp=3; IntAct=EBI-13345167, EBI-2130213;
CC Q8TDT2; Q8NHS1: CLDND2; NbExp=3; IntAct=EBI-13345167, EBI-11959453;
CC Q8TDT2; Q6ZS10: CLEC17A; NbExp=3; IntAct=EBI-13345167, EBI-11977093;
CC Q8TDT2; Q8NC01: CLEC1A; NbExp=3; IntAct=EBI-13345167, EBI-11996768;
CC Q8TDT2; A0A024R644: CLN5; NbExp=3; IntAct=EBI-13345167, EBI-12838990;
CC Q8TDT2; O95406: CNIH1; NbExp=3; IntAct=EBI-13345167, EBI-12172273;
CC Q8TDT2; Q4VAQ0: COL8A2; NbExp=3; IntAct=EBI-13345167, EBI-10241815;
CC Q8TDT2; P21964: COMT; NbExp=3; IntAct=EBI-13345167, EBI-372265;
CC Q8TDT2; P54108-2: CRISP3; NbExp=3; IntAct=EBI-13345167, EBI-18210151;
CC Q8TDT2; Q8N6G5: CSGALNACT2; NbExp=3; IntAct=EBI-13345167, EBI-10267100;
CC Q8TDT2; Q4LDR2: CTXN3; NbExp=3; IntAct=EBI-13345167, EBI-12019274;
CC Q8TDT2; P49447: CYB561; NbExp=3; IntAct=EBI-13345167, EBI-8646596;
CC Q8TDT2; Q8NBI2: CYB561A3; NbExp=3; IntAct=EBI-13345167, EBI-10269179;
CC Q8TDT2; O43169: CYB5B; NbExp=3; IntAct=EBI-13345167, EBI-1058710;
CC Q8TDT2; P00387: CYB5R3; NbExp=3; IntAct=EBI-13345167, EBI-1046040;
CC Q8TDT2; Q9BQA9: CYBC1; NbExp=3; IntAct=EBI-13345167, EBI-2680384;
CC Q8TDT2; Q8NET1: DEFB108B; NbExp=3; IntAct=EBI-13345167, EBI-13346443;
CC Q8TDT2; Q6ZPD8: DGAT2L6; NbExp=3; IntAct=EBI-13345167, EBI-12831978;
CC Q8TDT2; Q15125: EBP; NbExp=3; IntAct=EBI-13345167, EBI-3915253;
CC Q8TDT2; P56851: EDDM3B; NbExp=3; IntAct=EBI-13345167, EBI-10215665;
CC Q8TDT2; P52803: EFNA5; NbExp=3; IntAct=EBI-13345167, EBI-1753674;
CC Q8TDT2; P50402: EMD; NbExp=3; IntAct=EBI-13345167, EBI-489887;
CC Q8TDT2; Q9UKR5: ERG28; NbExp=3; IntAct=EBI-13345167, EBI-711490;
CC Q8TDT2; Q7L5A8: FA2H; NbExp=3; IntAct=EBI-13345167, EBI-11337888;
CC Q8TDT2; O75063: FAM20B; NbExp=3; IntAct=EBI-13345167, EBI-11090967;
CC Q8TDT2; Q96IV6: FAXDC2; NbExp=3; IntAct=EBI-13345167, EBI-12142299;
CC Q8TDT2; P37268: FDFT1; NbExp=3; IntAct=EBI-13345167, EBI-714550;
CC Q8TDT2; Q9BWH2: FUNDC2; NbExp=3; IntAct=EBI-13345167, EBI-714482;
CC Q8TDT2; Q14802-3: FXYD3; NbExp=3; IntAct=EBI-13345167, EBI-12175685;
CC Q8TDT2; P01350: GAST; NbExp=3; IntAct=EBI-13345167, EBI-3436637;
CC Q8TDT2; P29033: GJB2; NbExp=3; IntAct=EBI-13345167, EBI-3905204;
CC Q8TDT2; Q6ZVE7: GOLT1A; NbExp=3; IntAct=EBI-13345167, EBI-17231387;
CC Q8TDT2; Q9Y3E0: GOLT1B; NbExp=3; IntAct=EBI-13345167, EBI-4402607;
CC Q8TDT2; O14653: GOSR2; NbExp=3; IntAct=EBI-13345167, EBI-4401517;
CC Q8TDT2; Q8TDV0: GPR151; NbExp=3; IntAct=EBI-13345167, EBI-11955647;
CC Q8TDT2; Q8TDT2: GPR152; NbExp=3; IntAct=EBI-13345167, EBI-13345167;
CC Q8TDT2; O60883: GPR37L1; NbExp=3; IntAct=EBI-13345167, EBI-2927498;
CC Q8TDT2; Q9HCP6: HHATL; NbExp=3; IntAct=EBI-13345167, EBI-5916693;
CC Q8TDT2; P09601: HMOX1; NbExp=3; IntAct=EBI-13345167, EBI-2806151;
CC Q8TDT2; P30519: HMOX2; NbExp=3; IntAct=EBI-13345167, EBI-712096;
CC Q8TDT2; P32881: IFNA8; NbExp=3; IntAct=EBI-13345167, EBI-18211524;
CC Q8TDT2; P01344-3: IGF2; NbExp=3; IntAct=EBI-13345167, EBI-13334485;
CC Q8TDT2; P24593: IGFBP5; NbExp=3; IntAct=EBI-13345167, EBI-720480;
CC Q8TDT2; Q01638-2: IL1RL1; NbExp=3; IntAct=EBI-13345167, EBI-12838366;
CC Q8TDT2; Q9Y5U4: INSIG2; NbExp=3; IntAct=EBI-13345167, EBI-8503746;
CC Q8TDT2; Q8N5M9: JAGN1; NbExp=3; IntAct=EBI-13345167, EBI-10266796;
CC Q8TDT2; Q09470: KCNA1; NbExp=3; IntAct=EBI-13345167, EBI-8286599;
CC Q8TDT2; O15554: KCNN4; NbExp=3; IntAct=EBI-13345167, EBI-2924473;
CC Q8TDT2; P07942: LAMB1; NbExp=3; IntAct=EBI-13345167, EBI-949174;
CC Q8TDT2; O43561-2: LAT; NbExp=3; IntAct=EBI-13345167, EBI-8070286;
CC Q8TDT2; O95214: LEPROTL1; NbExp=3; IntAct=EBI-13345167, EBI-750776;
CC Q8TDT2; Q6ZUX7: LHFPL2; NbExp=3; IntAct=EBI-13345167, EBI-17566767;
CC Q8TDT2; Q8TAF8: LHFPL5; NbExp=3; IntAct=EBI-13345167, EBI-2820517;
CC Q8TDT2; Q16873: LTC4S; NbExp=3; IntAct=EBI-13345167, EBI-12241118;
CC Q8TDT2; P21145: MAL; NbExp=3; IntAct=EBI-13345167, EBI-3932027;
CC Q8TDT2; Q969L2: MAL2; NbExp=3; IntAct=EBI-13345167, EBI-944295;
CC Q8TDT2; Q9GZY8-5: MFF; NbExp=3; IntAct=EBI-13345167, EBI-11956541;
CC Q8TDT2; Q6N075: MFSD5; NbExp=3; IntAct=EBI-13345167, EBI-3920969;
CC Q8TDT2; Q6ZSS7: MFSD6; NbExp=3; IntAct=EBI-13345167, EBI-2858252;
CC Q8TDT2; A0A0C4DFN3: MGLL; NbExp=3; IntAct=EBI-13345167, EBI-12866138;
CC Q8TDT2; O14880: MGST3; NbExp=3; IntAct=EBI-13345167, EBI-724754;
CC Q8TDT2; Q15546: MMD; NbExp=3; IntAct=EBI-13345167, EBI-17873222;
CC Q8TDT2; O75425: MOSPD3; NbExp=3; IntAct=EBI-13345167, EBI-12179105;
CC Q8TDT2; Q5J8X5: MS4A13; NbExp=3; IntAct=EBI-13345167, EBI-12070086;
CC Q8TDT2; A6NDP7: MYADML2; NbExp=3; IntAct=EBI-13345167, EBI-17641390;
CC Q8TDT2; Q9UHE5: NAT8; NbExp=3; IntAct=EBI-13345167, EBI-2863634;
CC Q8TDT2; Q9NX14: NDUFB11; NbExp=3; IntAct=EBI-13345167, EBI-1246182;
CC Q8TDT2; Q99519: NEU1; NbExp=3; IntAct=EBI-13345167, EBI-721517;
CC Q8TDT2; Q9NZG7: NINJ2; NbExp=3; IntAct=EBI-13345167, EBI-10317425;
CC Q8TDT2; Q0D2K0: NIPAL4; NbExp=3; IntAct=EBI-13345167, EBI-9550165;
CC Q8TDT2; Q8N912: NRAC; NbExp=3; IntAct=EBI-13345167, EBI-12051377;
CC Q8TDT2; Q9P0S3: ORMDL1; NbExp=3; IntAct=EBI-13345167, EBI-1054848;
CC Q8TDT2; Q8N138: ORMDL3; NbExp=3; IntAct=EBI-13345167, EBI-721750;
CC Q8TDT2; I3L0A0: PEDS1-UBE2V1; NbExp=3; IntAct=EBI-13345167, EBI-12213001;
CC Q8TDT2; Q9Y5Y5: PEX16; NbExp=3; IntAct=EBI-13345167, EBI-981985;
CC Q8TDT2; Q9UHJ9-5: PGAP2; NbExp=3; IntAct=EBI-13345167, EBI-12092917;
CC Q8TDT2; Q07326: PIGF; NbExp=3; IntAct=EBI-13345167, EBI-17180304;
CC Q8TDT2; Q13526: PIN1; NbExp=3; IntAct=EBI-13345167, EBI-714158;
CC Q8TDT2; P26678: PLN; NbExp=3; IntAct=EBI-13345167, EBI-692836;
CC Q8TDT2; P54315: PNLIPRP1; NbExp=3; IntAct=EBI-13345167, EBI-8652812;
CC Q8TDT2; O60831: PRAF2; NbExp=3; IntAct=EBI-13345167, EBI-2506064;
CC Q8TDT2; Q8N271: PROM2; NbExp=3; IntAct=EBI-13345167, EBI-18210782;
CC Q8TDT2; Q16849-3: PTPRN; NbExp=3; IntAct=EBI-13345167, EBI-10200782;
CC Q8TDT2; Q9UI14: RABAC1; NbExp=3; IntAct=EBI-13345167, EBI-712367;
CC Q8TDT2; Q8N0V3: RBFA; NbExp=3; IntAct=EBI-13345167, EBI-3232108;
CC Q8TDT2; Q96HR9-2: REEP6; NbExp=3; IntAct=EBI-13345167, EBI-14065960;
CC Q8TDT2; Q9HCK4: ROBO2; NbExp=3; IntAct=EBI-13345167, EBI-399800;
CC Q8TDT2; O95197-3: RTN3; NbExp=3; IntAct=EBI-13345167, EBI-11525735;
CC Q8TDT2; Q5QGT7: RTP2; NbExp=3; IntAct=EBI-13345167, EBI-10244780;
CC Q8TDT2; Q9NTJ5: SACM1L; NbExp=3; IntAct=EBI-13345167, EBI-3917235;
CC Q8TDT2; Q969E2: SCAMP4; NbExp=3; IntAct=EBI-13345167, EBI-4403649;
CC Q8TDT2; O00767: SCD; NbExp=3; IntAct=EBI-13345167, EBI-2684237;
CC Q8TDT2; O75396: SEC22B; NbExp=3; IntAct=EBI-13345167, EBI-1058865;
CC Q8TDT2; O75920: SERF1B; NbExp=3; IntAct=EBI-13345167, EBI-2115181;
CC Q8TDT2; Q8N6R1: SERP2; NbExp=3; IntAct=EBI-13345167, EBI-749270;
CC Q8TDT2; O95562: SFT2D2; NbExp=3; IntAct=EBI-13345167, EBI-4402330;
CC Q8TDT2; P11686: SFTPC; NbExp=3; IntAct=EBI-13345167, EBI-10197617;
CC Q8TDT2; Q14973: SLC10A1; NbExp=3; IntAct=EBI-13345167, EBI-3923031;
CC Q8TDT2; Q9UKG4: SLC13A4; NbExp=3; IntAct=EBI-13345167, EBI-12808018;
CC Q8TDT2; Q99726: SLC30A3; NbExp=3; IntAct=EBI-13345167, EBI-10294651;
CC Q8TDT2; Q96G79: SLC35A4; NbExp=3; IntAct=EBI-13345167, EBI-12363689;
CC Q8TDT2; P78383: SLC35B1; NbExp=3; IntAct=EBI-13345167, EBI-12147661;
CC Q8TDT2; Q969S0: SLC35B4; NbExp=3; IntAct=EBI-13345167, EBI-10281213;
CC Q8TDT2; Q9NQQ7-3: SLC35C2; NbExp=3; IntAct=EBI-13345167, EBI-17295964;
CC Q8TDT2; Q8N357: SLC35F6; NbExp=3; IntAct=EBI-13345167, EBI-713484;
CC Q8TDT2; Q9H2H9: SLC38A1; NbExp=3; IntAct=EBI-13345167, EBI-9978441;
CC Q8TDT2; Q9NVC3: SLC38A7; NbExp=3; IntAct=EBI-13345167, EBI-10314552;
CC Q8TDT2; Q9NP94: SLC39A2; NbExp=3; IntAct=EBI-13345167, EBI-12898013;
CC Q8TDT2; Q8IVJ1: SLC41A1; NbExp=3; IntAct=EBI-13345167, EBI-12266234;
CC Q8TDT2; Q6ZP29-3: SLC66A1; NbExp=3; IntAct=EBI-13345167, EBI-12889586;
CC Q8TDT2; Q8N2U9: SLC66A2; NbExp=3; IntAct=EBI-13345167, EBI-3907610;
CC Q8TDT2; P30825: SLC7A1; NbExp=3; IntAct=EBI-13345167, EBI-4289564;
CC Q8TDT2; Q9NRQ5: SMCO4; NbExp=3; IntAct=EBI-13345167, EBI-8640191;
CC Q8TDT2; P02808: STATH; NbExp=3; IntAct=EBI-13345167, EBI-738687;
CC Q8TDT2; P61266: STX1B; NbExp=3; IntAct=EBI-13345167, EBI-9071709;
CC Q8TDT2; Q13277: STX3; NbExp=3; IntAct=EBI-13345167, EBI-1394295;
CC Q8TDT2; Q12846: STX4; NbExp=3; IntAct=EBI-13345167, EBI-744942;
CC Q8TDT2; Q13190: STX5; NbExp=3; IntAct=EBI-13345167, EBI-714206;
CC Q8TDT2; Q9UNK0: STX8; NbExp=3; IntAct=EBI-13345167, EBI-727240;
CC Q8TDT2; Q9BQS2-2: SYT15; NbExp=3; IntAct=EBI-13345167, EBI-13373352;
CC Q8TDT2; Q03518: TAP1; NbExp=3; IntAct=EBI-13345167, EBI-747259;
CC Q8TDT2; Q9Y6I9: TEX264; NbExp=3; IntAct=EBI-13345167, EBI-10329860;
CC Q8TDT2; P02786: TFRC; NbExp=3; IntAct=EBI-13345167, EBI-355727;
CC Q8TDT2; C9JKN6: THSD7B; NbExp=3; IntAct=EBI-13345167, EBI-17192156;
CC Q8TDT2; Q9NPL8: TIMMDC1; NbExp=3; IntAct=EBI-13345167, EBI-6268651;
CC Q8TDT2; Q96DZ7: TM4SF19; NbExp=3; IntAct=EBI-13345167, EBI-6448756;
CC Q8TDT2; Q9NV29: TMEM100; NbExp=3; IntAct=EBI-13345167, EBI-8644968;
CC Q8TDT2; A0PK00: TMEM120B; NbExp=3; IntAct=EBI-13345167, EBI-10171534;
CC Q8TDT2; Q5BJH2-2: TMEM128; NbExp=3; IntAct=EBI-13345167, EBI-10694905;
CC Q8TDT2; Q9NV12: TMEM140; NbExp=3; IntAct=EBI-13345167, EBI-2844246;
CC Q8TDT2; Q9NUH8: TMEM14B; NbExp=3; IntAct=EBI-13345167, EBI-8638294;
CC Q8TDT2; Q9P0S9: TMEM14C; NbExp=3; IntAct=EBI-13345167, EBI-2339195;
CC Q8TDT2; Q5SNT2-2: TMEM201; NbExp=3; IntAct=EBI-13345167, EBI-11994282;
CC Q8TDT2; Q9BTX3: TMEM208; NbExp=3; IntAct=EBI-13345167, EBI-12876824;
CC Q8TDT2; A2RU14: TMEM218; NbExp=3; IntAct=EBI-13345167, EBI-10173151;
CC Q8TDT2; Q5W0B7: TMEM236; NbExp=3; IntAct=EBI-13345167, EBI-13378608;
CC Q8TDT2; Q96Q45-2: TMEM237; NbExp=3; IntAct=EBI-13345167, EBI-10982110;
CC Q8TDT2; Q9BU79: TMEM243; NbExp=3; IntAct=EBI-13345167, EBI-12887458;
CC Q8TDT2; Q8TBM7: TMEM254; NbExp=3; IntAct=EBI-13345167, EBI-11956809;
CC Q8TDT2; Q69YG0: TMEM42; NbExp=3; IntAct=EBI-13345167, EBI-12038591;
CC Q8TDT2; P56557: TMEM50B; NbExp=3; IntAct=EBI-13345167, EBI-12366453;
CC Q8TDT2; Q969K7: TMEM54; NbExp=3; IntAct=EBI-13345167, EBI-3922833;
CC Q8TDT2; Q9H2L4: TMEM60; NbExp=3; IntAct=EBI-13345167, EBI-2852148;
CC Q8TDT2; Q5BJF2: TMEM97; NbExp=3; IntAct=EBI-13345167, EBI-12111910;
CC Q8TDT2; Q6ZT21: TMPPE; NbExp=3; IntAct=EBI-13345167, EBI-11724433;
CC Q8TDT2; O14798: TNFRSF10C; NbExp=3; IntAct=EBI-13345167, EBI-717441;
CC Q8TDT2; A0AVG3: TSNARE1; NbExp=3; IntAct=EBI-13345167, EBI-12003468;
CC Q8TDT2; Q86UF1: TSPAN33; NbExp=3; IntAct=EBI-13345167, EBI-12045841;
CC Q8TDT2; P41732: TSPAN7; NbExp=3; IntAct=EBI-13345167, EBI-1042779;
CC Q8TDT2; Q5TGU0: TSPO2; NbExp=3; IntAct=EBI-13345167, EBI-12195249;
CC Q8TDT2; Q9Y5Z9: UBIAD1; NbExp=3; IntAct=EBI-13345167, EBI-2819725;
CC Q8TDT2; Q53HI1: UNC50; NbExp=3; IntAct=EBI-13345167, EBI-7601760;
CC Q8TDT2; P23763-3: VAMP1; NbExp=3; IntAct=EBI-13345167, EBI-12097582;
CC Q8TDT2; O75379: VAMP4; NbExp=3; IntAct=EBI-13345167, EBI-744953;
CC Q8TDT2; O95183: VAMP5; NbExp=3; IntAct=EBI-13345167, EBI-10191195;
CC Q8TDT2; Q9BQB6: VKORC1; NbExp=3; IntAct=EBI-13345167, EBI-6256462;
CC Q8TDT2; Q9Y548: YIPF1; NbExp=3; IntAct=EBI-13345167, EBI-7850136;
CC Q8TDT2; Q9BSR8: YIPF4; NbExp=3; IntAct=EBI-13345167, EBI-751253;
CC Q8TDT2; Q96EC8: YIPF6; NbExp=3; IntAct=EBI-13345167, EBI-751210;
CC Q8TDT2; Q96MV8: ZDHHC15; NbExp=3; IntAct=EBI-13345167, EBI-12837904;
CC Q8TDT2; Q96FB2; NbExp=3; IntAct=EBI-13345167, EBI-2857623;
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY569571; AAS76893.1; -; mRNA.
DR EMBL; AB083620; BAB89333.1; -; Genomic_DNA.
DR EMBL; AB065853; BAC06071.1; -; Genomic_DNA.
DR EMBL; BC119779; AAI19780.1; -; mRNA.
DR EMBL; BC122869; AAI22870.1; -; mRNA.
DR EMBL; AY255600; AAO85112.1; -; mRNA.
DR CCDS; CCDS8165.1; -.
DR RefSeq; NP_996880.1; NM_206997.1.
DR AlphaFoldDB; Q8TDT2; -.
DR SMR; Q8TDT2; -.
DR BioGRID; 133448; 195.
DR IntAct; Q8TDT2; 190.
DR STRING; 9606.ENSP00000310255; -.
DR ChEMBL; CHEMBL4523900; -.
DR iPTMnet; Q8TDT2; -.
DR PhosphoSitePlus; Q8TDT2; -.
DR BioMuta; GPR152; -.
DR DMDM; 48428096; -.
DR PaxDb; Q8TDT2; -.
DR PeptideAtlas; Q8TDT2; -.
DR PRIDE; Q8TDT2; -.
DR Antibodypedia; 16520; 165 antibodies from 28 providers.
DR DNASU; 390212; -.
DR Ensembl; ENST00000312457.2; ENSP00000310255.2; ENSG00000175514.2.
DR GeneID; 390212; -.
DR KEGG; hsa:390212; -.
DR MANE-Select; ENST00000312457.2; ENSP00000310255.2; NM_206997.1; NP_996880.1.
DR UCSC; uc001olm.3; human.
DR CTD; 390212; -.
DR DisGeNET; 390212; -.
DR GeneCards; GPR152; -.
DR HGNC; HGNC:23622; GPR152.
DR HPA; ENSG00000175514; Not detected.
DR neXtProt; NX_Q8TDT2; -.
DR OpenTargets; ENSG00000175514; -.
DR PharmGKB; PA134897297; -.
DR VEuPathDB; HostDB:ENSG00000175514; -.
DR eggNOG; ENOG502SP7R; Eukaryota.
DR GeneTree; ENSGT01030000234639; -.
DR HOGENOM; CLU_587370_0_0_1; -.
DR InParanoid; Q8TDT2; -.
DR OMA; SPFLCLM; -.
DR OrthoDB; 1256901at2759; -.
DR PhylomeDB; Q8TDT2; -.
DR TreeFam; TF338313; -.
DR PathwayCommons; Q8TDT2; -.
DR SignaLink; Q8TDT2; -.
DR BioGRID-ORCS; 390212; 10 hits in 1060 CRISPR screens.
DR GeneWiki; GPR152; -.
DR GenomeRNAi; 390212; -.
DR Pharos; Q8TDT2; Tbio.
DR PRO; PR:Q8TDT2; -.
DR Proteomes; UP000005640; Chromosome 11.
DR RNAct; Q8TDT2; protein.
DR Bgee; ENSG00000175514; Expressed in granulocyte and 8 other tissues.
DR ExpressionAtlas; Q8TDT2; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR027313; GPR152_orphan_prd.
DR InterPro; IPR026234; MRGPCRFAMILY.
DR PANTHER; PTHR11334; PTHR11334; 1.
DR PANTHER; PTHR11334:SF1; PTHR11334:SF1; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Membrane;
KW Receptor; Reference proteome; Transducer; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..470
FT /note="Probable G-protein coupled receptor 152"
FT /id="PRO_0000069635"
FT TOPO_DOM 1..33
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 34..54
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..65
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 87..105
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 127..148
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..169
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 170..194
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 195..215
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 216..257
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 279..281
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 282..302
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 303..470
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 104..182
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT VARIANT 317
FT /note="L -> V (in dbSNP:rs1638559)"
FT /id="VAR_059323"
SQ SEQUENCE 470 AA; 50962 MW; 8B566AE95D9D79B4 CRC64;
MDTTMEADLG ATGHRPRTEL DDEDSYPQGG WDTVFLVALL LLGLPANGLM AWLAGSQARH
GAGTRLALLL LSLALSDFLF LAAAAFQILE IRHGGHWPLG TAACRFYYFL WGVSYSSGLF
LLAALSLDRC LLALCPHWYP GHRPVRLPLW VCAGVWVLAT LFSVPWLVFP EAAVWWYDLV
ICLDFWDSEE LSLRMLEVLG GFLPFLLLLV CHVLTQATAC RTCHRQQQPA ACRGFARVAR
TILSAYVVLR LPYQLAQLLY LAFLWDVYSG YLLWEALVYS DYLILLNSCL SPFLCLMASA
DLRTLLRSVL SSFAAALCEE RPGSFTPTEP QTQLDSEGPT LPEPMAEAQS QMDPVAQPQV
NPTLQPRSDP TAQPQLNPTA QPQSDPTAQP QLNLMAQPQS DSVAQPQADT NVQTPAPAAS
SVPSPCDEAS PTPSSHPTPG ALEDPATPPA SEGESPSSTP PEAAPGAGPT
